A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome
Macrophage Activation Syndrome (MAS) is a rare form of Haemophagocytic Lymphohistiocytosis (HLH) associated with rheumatologic conditions. It is characterised by haemophagocytosis and cytokine overproduction, resulting from the activation and uncontrolled proliferation of T lymphocytes and macroph...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8518/20902_CE[Ra]_F(P)_PF1(ASAK)_PFA(AK)_PF2(PEK).pdf |
| Summary: | Macrophage Activation Syndrome (MAS) is a rare form of Haemophagocytic Lymphohistiocytosis (HLH) associated with rheumatologic
conditions. It is characterised by haemophagocytosis and cytokine overproduction, resulting from the activation and uncontrolled
proliferation of T lymphocytes and macrophages. The patient being reported is an elderly female with Rheumatoid Arthritis (RA), who
presented with fever and was found to have MAS. She later developed Acute Respiratory Distress Syndrome (ARDS) and died. Such a
scenario has rarely been reported. |
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| ISSN: | 2249-782X 0973-709X |