A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome
Macrophage Activation Syndrome (MAS) is a rare form of Haemophagocytic Lymphohistiocytosis (HLH) associated with rheumatologic conditions. It is characterised by haemophagocytosis and cytokine overproduction, resulting from the activation and uncontrolled proliferation of T lymphocytes and macroph...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-09-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8518/20902_CE[Ra]_F(P)_PF1(ASAK)_PFA(AK)_PF2(PEK).pdf |
| _version_ | 1818211593465364480 |
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| author | Robin George Manappallil |
| author_facet | Robin George Manappallil |
| author_sort | Robin George Manappallil |
| collection | DOAJ |
| description | Macrophage Activation Syndrome (MAS) is a rare form of Haemophagocytic Lymphohistiocytosis (HLH) associated with rheumatologic
conditions. It is characterised by haemophagocytosis and cytokine overproduction, resulting from the activation and uncontrolled
proliferation of T lymphocytes and macrophages. The patient being reported is an elderly female with Rheumatoid Arthritis (RA), who
presented with fever and was found to have MAS. She later developed Acute Respiratory Distress Syndrome (ARDS) and died. Such a
scenario has rarely been reported. |
| first_indexed | 2024-12-12T05:34:58Z |
| format | Article |
| id | doaj.art-672e2dbdf8184081b8121d0e5747c51b |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-12T05:34:58Z |
| publishDate | 2016-09-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-672e2dbdf8184081b8121d0e5747c51b2022-12-22T00:36:11ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-09-01109OD11OD1210.7860/JCDR/2016/20902.8518A Case of Macrophage Activation Syndrome with Acute Respiratory Distress SyndromeRobin George Manappallil0Consultant – Physician, Department of Medicine, National Hospital, Calicut, Kerala, India.Macrophage Activation Syndrome (MAS) is a rare form of Haemophagocytic Lymphohistiocytosis (HLH) associated with rheumatologic conditions. It is characterised by haemophagocytosis and cytokine overproduction, resulting from the activation and uncontrolled proliferation of T lymphocytes and macrophages. The patient being reported is an elderly female with Rheumatoid Arthritis (RA), who presented with fever and was found to have MAS. She later developed Acute Respiratory Distress Syndrome (ARDS) and died. Such a scenario has rarely been reported.https://jcdr.net/articles/PDF/8518/20902_CE[Ra]_F(P)_PF1(ASAK)_PFA(AK)_PF2(PEK).pdfhaemophagocytic lymphohistiocytosisrheumatoid arthritis |
| spellingShingle | Robin George Manappallil A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome Journal of Clinical and Diagnostic Research haemophagocytic lymphohistiocytosis rheumatoid arthritis |
| title | A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome |
| title_full | A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome |
| title_fullStr | A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome |
| title_full_unstemmed | A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome |
| title_short | A Case of Macrophage Activation Syndrome with Acute Respiratory Distress Syndrome |
| title_sort | case of macrophage activation syndrome with acute respiratory distress syndrome |
| topic | haemophagocytic lymphohistiocytosis rheumatoid arthritis |
| url | https://jcdr.net/articles/PDF/8518/20902_CE[Ra]_F(P)_PF1(ASAK)_PFA(AK)_PF2(PEK).pdf |
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