Cerebral palsy in preterm infants
Background/Aim. Cerebral palsy (CP) is one of the leading causes of neurological impairment in childhood. Preterm birth is a significant risk factor in the occurrence of CP. Clinical outcomes may include impairment of gross motor function and intellectual abilities, visual impairment and...
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| Format: | Article |
| Language: | English |
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Military Health Department, Ministry of Defance, Serbia
2016-01-01
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| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600019D.pdf |
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| author | Demeši-Drljan Čila Mikov Aleksandra Filipović Karmela Tomašević-Todorović Snežana Knežević Aleksandar Krasnik Rastislava |
| author_facet | Demeši-Drljan Čila Mikov Aleksandra Filipović Karmela Tomašević-Todorović Snežana Knežević Aleksandar Krasnik Rastislava |
| author_sort | Demeši-Drljan Čila |
| collection | DOAJ |
| description | Background/Aim. Cerebral palsy (CP) is one of the leading causes of
neurological impairment in childhood. Preterm birth is a significant risk
factor in the occurrence of CP. Clinical outcomes may include impairment of
gross motor function and intellectual abilities, visual impairment and
epilepsy. The aim of this study was to examine the relationships among
gestational age, type of CP, functional ability and associated conditions.
Methods. The sample size was 206 children with CP. The data were obtained
from medical records and included gestational age at birth, clinical
characteristics of CP and associated conditions. Clinical CP type was
determined according to Surveillance of Cerebral Palsy in Europe (SCPE) and
topographically. Gross motor function abilities were evaluated according to
the Gross Motor Function Classification System (GMFCS). Results. More than
half of the children with CP were born prematurely (54.4%). Statistically
significant difference was noted with respect to the distribution of various
clinical types of CP in relation to gestational age (p < 0.001). In the group
with spastic bilateral CP type, there is a greater proportion of children
born preterm. Statistically significant difference was noted in the
functional classification based on GMFCS in terms of gestational age (p =
0.049), children born at earlier gestational age are classified at a higher
GMFCS level of functional limitation. The greatest percentage of children
(70.0%) affected by two or more associated conditions was found in the group
that had extremely preterm birth, and that number declined with increasing
maturity at birth. Epilepsy was more prevalent in children born at greater
gestational age, and this difference in distribution was statistically
significant (p = 0.032). Conclusion. The application of antenatal and
postnatal protection of preterm children should be a significant component of
the CP prevention strategy. [Projekat Ministarstva nauke Republike Srbije,
br. 41012 i br. 44008] |
| first_indexed | 2024-12-21T06:17:53Z |
| format | Article |
| id | doaj.art-672ea311137348f6a88c26b5ade2f506 |
| institution | Directory Open Access Journal |
| issn | 0042-8450 2406-0720 |
| language | English |
| last_indexed | 2024-12-21T06:17:53Z |
| publishDate | 2016-01-01 |
| publisher | Military Health Department, Ministry of Defance, Serbia |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj.art-672ea311137348f6a88c26b5ade2f5062022-12-21T19:13:20ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202016-01-0173434334810.2298/VSP140321019D0042-84501600019DCerebral palsy in preterm infantsDemeši-Drljan Čila0Mikov Aleksandra1Filipović Karmela2Tomašević-Todorović Snežana3Knežević Aleksandar4Krasnik Rastislava5Clinical Center of Vojvodina, Institute for Children and Youth Health Care of Vojvodina, Novi SadClinical Center of Vojvodina, Institute for Children and Youth Health Care of Vojvodina, Novi SadClinical Center of Vojvodina, Special Hospital for Rheumathic Diseases, Novi SadClinical Center of Vojvodina, Faculty of Medicine, Novi SadClinical Center of Vojvodina, Faculty of Medicine, Novi SadClinical Center of Vojvodina, Institute for Children and Youth Health Care of Vojvodina, Novi SadBackground/Aim. Cerebral palsy (CP) is one of the leading causes of neurological impairment in childhood. Preterm birth is a significant risk factor in the occurrence of CP. Clinical outcomes may include impairment of gross motor function and intellectual abilities, visual impairment and epilepsy. The aim of this study was to examine the relationships among gestational age, type of CP, functional ability and associated conditions. Methods. The sample size was 206 children with CP. The data were obtained from medical records and included gestational age at birth, clinical characteristics of CP and associated conditions. Clinical CP type was determined according to Surveillance of Cerebral Palsy in Europe (SCPE) and topographically. Gross motor function abilities were evaluated according to the Gross Motor Function Classification System (GMFCS). Results. More than half of the children with CP were born prematurely (54.4%). Statistically significant difference was noted with respect to the distribution of various clinical types of CP in relation to gestational age (p < 0.001). In the group with spastic bilateral CP type, there is a greater proportion of children born preterm. Statistically significant difference was noted in the functional classification based on GMFCS in terms of gestational age (p = 0.049), children born at earlier gestational age are classified at a higher GMFCS level of functional limitation. The greatest percentage of children (70.0%) affected by two or more associated conditions was found in the group that had extremely preterm birth, and that number declined with increasing maturity at birth. Epilepsy was more prevalent in children born at greater gestational age, and this difference in distribution was statistically significant (p = 0.032). Conclusion. The application of antenatal and postnatal protection of preterm children should be a significant component of the CP prevention strategy. [Projekat Ministarstva nauke Republike Srbije, br. 41012 i br. 44008]http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600019D.pdfcerebral palsyrisk factorsinfant, premature |
| spellingShingle | Demeši-Drljan Čila Mikov Aleksandra Filipović Karmela Tomašević-Todorović Snežana Knežević Aleksandar Krasnik Rastislava Cerebral palsy in preterm infants Vojnosanitetski Pregled cerebral palsy risk factors infant, premature |
| title | Cerebral palsy in preterm infants |
| title_full | Cerebral palsy in preterm infants |
| title_fullStr | Cerebral palsy in preterm infants |
| title_full_unstemmed | Cerebral palsy in preterm infants |
| title_short | Cerebral palsy in preterm infants |
| title_sort | cerebral palsy in preterm infants |
| topic | cerebral palsy risk factors infant, premature |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2016/0042-84501600019D.pdf |
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