Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations

Development of a 3-Dimensional Model to Study Right Heart Dysfunction in Pulmonary Arterial Hypertension: First Observations

Pulmonary arterial hypertension (PAH) patients eventually die of right heart failure (RHF). Currently, there is no suitable pre-clinical model to study PAH. Therefore, we aim to develop a right heart dysfunction (RHD) model using the 3-dimensional engineered heart tissue (EHT) approach and cardiomyo...

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Bibliographic Details
Main Authors: Aida Llucià-Valldeperas, Rowan Smal, Fjodor T. Bekedam, Margaux Cé, Xiaoke Pan, Xue D. Manz, Paul J. M. Wijnker, Anton Vonk-Noordegraaf, Harm J. Bogaard, Marie-Jose Goumans, Frances S. de Man
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
pulmonary arterial hypertension
right heart dysfunction
induced pluripotent stem cells
engineered heart tissue
Online Access:https://www.mdpi.com/2073-4409/10/12/3595

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https://www.mdpi.com/2073-4409/10/12/3595

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