Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review

Residual neuromuscular block (RNMB) remains a significant safety concern for patients throughout the perioperative period and is still widely under-recognized by perioperative healthcare professionals. Current literature suggests an association between RNMB and an increased risk of postoperative pul...

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Main Authors: Franziska Elisabeth Blum, Andrew R. Locke, Naveen Nathan, Jeffrey Katz, David Bissing, Mohammed Minhaj, Steven B. Greenberg
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/13/3/861
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author Franziska Elisabeth Blum
Andrew R. Locke
Naveen Nathan
Jeffrey Katz
David Bissing
Mohammed Minhaj
Steven B. Greenberg
author_facet Franziska Elisabeth Blum
Andrew R. Locke
Naveen Nathan
Jeffrey Katz
David Bissing
Mohammed Minhaj
Steven B. Greenberg
author_sort Franziska Elisabeth Blum
collection DOAJ
description Residual neuromuscular block (RNMB) remains a significant safety concern for patients throughout the perioperative period and is still widely under-recognized by perioperative healthcare professionals. Current literature suggests an association between RNMB and an increased risk of postoperative pulmonary complications, a prolonged length of stay in the post anesthesia care unit (PACU), and decreased patient satisfaction. The 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade provide guidance for the use of quantitative neuromuscular monitoring coupled with neuromuscular reversal to recognize and reduce the incidence of RNMB. Using sugammadex for the reversal of neuromuscular block as well as quantitative neuromuscular monitoring to quantify the degree of neuromuscular block may significantly reduce the risk of RNMB among patients undergoing general anesthesia. Studies are forthcoming to investigate how using neuromuscular blocking agent reversal with quantitative monitoring of the neuromuscular block may further improve perioperative patient safety.
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spelling doaj.art-673663f46e7445a08fd113483b5ffb452024-02-09T15:16:32ZengMDPI AGJournal of Clinical Medicine2077-03832024-02-0113386110.3390/jcm13030861Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive ReviewFranziska Elisabeth Blum0Andrew R. Locke1Naveen Nathan2Jeffrey Katz3David Bissing4Mohammed Minhaj5Steven B. Greenberg6Department of Internal Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USADepartment of Anesthesiology, Critical Care, and Pain Medicine, NorthShore University HealthSystem, Evanston, IL 60201, USAResidual neuromuscular block (RNMB) remains a significant safety concern for patients throughout the perioperative period and is still widely under-recognized by perioperative healthcare professionals. Current literature suggests an association between RNMB and an increased risk of postoperative pulmonary complications, a prolonged length of stay in the post anesthesia care unit (PACU), and decreased patient satisfaction. The 2023 American Society of Anesthesiologists Practice Guidelines for Monitoring and Antagonism of Neuromuscular Blockade provide guidance for the use of quantitative neuromuscular monitoring coupled with neuromuscular reversal to recognize and reduce the incidence of RNMB. Using sugammadex for the reversal of neuromuscular block as well as quantitative neuromuscular monitoring to quantify the degree of neuromuscular block may significantly reduce the risk of RNMB among patients undergoing general anesthesia. Studies are forthcoming to investigate how using neuromuscular blocking agent reversal with quantitative monitoring of the neuromuscular block may further improve perioperative patient safety.https://www.mdpi.com/2077-0383/13/3/861anesthesiaperioperative careresidual neuromuscular blockquantitative monitoringneuromuscular blocking agent
spellingShingle Franziska Elisabeth Blum
Andrew R. Locke
Naveen Nathan
Jeffrey Katz
David Bissing
Mohammed Minhaj
Steven B. Greenberg
Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
Journal of Clinical Medicine
anesthesia
perioperative care
residual neuromuscular block
quantitative monitoring
neuromuscular blocking agent
title Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
title_full Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
title_fullStr Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
title_full_unstemmed Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
title_short Residual Neuromuscular Block Remains a Safety Concern for Perioperative Healthcare Professionals: A Comprehensive Review
title_sort residual neuromuscular block remains a safety concern for perioperative healthcare professionals a comprehensive review
topic anesthesia
perioperative care
residual neuromuscular block
quantitative monitoring
neuromuscular blocking agent
url https://www.mdpi.com/2077-0383/13/3/861
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