A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy

Pulmonary hyalinising granuloma is a very rare disease often presenting as multiple smooth rounded nodules within the lung parenchyma and mimicking metastatic disease. Solitary pulmonary hyalinising granuloma is an even rarer subgroup, and to our knowledge, there have been no endoluminal pulmonary h...

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Main Authors: Jeremy LC Smelt, Brendan Madden, John Du Parcq, Ian Hunt
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X20967175
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author Jeremy LC Smelt
Brendan Madden
John Du Parcq
Ian Hunt
author_facet Jeremy LC Smelt
Brendan Madden
John Du Parcq
Ian Hunt
author_sort Jeremy LC Smelt
collection DOAJ
description Pulmonary hyalinising granuloma is a very rare disease often presenting as multiple smooth rounded nodules within the lung parenchyma and mimicking metastatic disease. Solitary pulmonary hyalinising granuloma is an even rarer subgroup, and to our knowledge, there have been no endoluminal pulmonary hyalinising granulomas reported. A 36-year-old female non-smoker with no significant past medical history presented with a persistent cough and was found to have a right lower lobe bronchial lesion causing lower lobe obstruction. After multiple failed attempts at tissue diagnosis from both percutaneous and endobronchial biopsies, and with worsening haemoptysis, the patient underwent a right thoracotomy and lower bilobectomy. The histopathology was reported as a solitary endobronchial pulmonary hyalinising granuloma. Although benign in nature, tissue diagnosis can be difficult in these lesions, especially when presenting as a solitary mass in a central location. This report demonstrates that these lesions can also be found endobronchially necessitating parenchymal resection for diagnosis and obstructive symptoms.
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spelling doaj.art-6736bf782ca24de0b47ab4b926c8c4dd2022-12-22T00:34:39ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2020-10-01810.1177/2050313X20967175A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomyJeremy LC Smelt0Brendan Madden1John Du Parcq2Ian Hunt3Department of Thoracic Surgery, St George’s Hospital NHS Foundation Trust, London, UKDepartment of Thoracic Surgery, St George’s Hospital NHS Foundation Trust, London, UKDepartment of Histopathology, St George’s Hospital NHS Foundation Trust, London, UKDepartment of Thoracic Surgery, St George’s Hospital NHS Foundation Trust, London, UKPulmonary hyalinising granuloma is a very rare disease often presenting as multiple smooth rounded nodules within the lung parenchyma and mimicking metastatic disease. Solitary pulmonary hyalinising granuloma is an even rarer subgroup, and to our knowledge, there have been no endoluminal pulmonary hyalinising granulomas reported. A 36-year-old female non-smoker with no significant past medical history presented with a persistent cough and was found to have a right lower lobe bronchial lesion causing lower lobe obstruction. After multiple failed attempts at tissue diagnosis from both percutaneous and endobronchial biopsies, and with worsening haemoptysis, the patient underwent a right thoracotomy and lower bilobectomy. The histopathology was reported as a solitary endobronchial pulmonary hyalinising granuloma. Although benign in nature, tissue diagnosis can be difficult in these lesions, especially when presenting as a solitary mass in a central location. This report demonstrates that these lesions can also be found endobronchially necessitating parenchymal resection for diagnosis and obstructive symptoms.https://doi.org/10.1177/2050313X20967175
spellingShingle Jeremy LC Smelt
Brendan Madden
John Du Parcq
Ian Hunt
A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
SAGE Open Medical Case Reports
title A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
title_full A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
title_fullStr A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
title_full_unstemmed A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
title_short A rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
title_sort rare solitary and endobronchial pulmonary hyalinising granuloma requiring bilobectomy
url https://doi.org/10.1177/2050313X20967175
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