Malignant clonal evolution drives multiple myeloma cellular ecological diversity and microenvironment reprogramming

Malignant clonal evolution drives multiple myeloma cellular ecological diversity and microenvironment reprogramming

Abstract Background Multiple myeloma (MM) is a heterogeneous disease with different patterns of clonal evolution and a complex tumor microenvironment, representing a challenge for clinicians and pathologists to understand and dissect the contribution and impact of polyclonality on tumor progression....

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Bibliographic Details
Main Authors:	Yuanzheng Liang, Haiyan He, Weida Wang, Henan Wang, Shaowen Mo, Ruiying Fu, Xindi Liu, Qiong Song, Zhongjun Xia, Liang Wang
Format:	Article
Language:	English
Published:	BMC 2022-09-01
Series:	Molecular Cancer
Subjects:	Multiple myeloma Malignant clonal evolution Cellular ecological diversity Microenvironment reprogramming Cell heterogeneity
Online Access:	https://doi.org/10.1186/s12943-022-01648-z

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