Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure
Ovarian hyperstimulation syndrome (OHSS) was first described in 1960. It may occur as a complication of gonadotropin hormone therapy during assisted pregnancy or for primary infertility. A 26-year-old female patient with polycystic ovarian syndrome and primary infertility was treated to conceive. Sh...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2016-08-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | http://www.karger.com/Article/FullText/446766 |
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| author | Muhammad Abdul Mabood Khalil Muhammad Salman Ghazni Jackson Tan Nazish Naseer Muhammad Ashhad Ullah Khalil |
| author_facet | Muhammad Abdul Mabood Khalil Muhammad Salman Ghazni Jackson Tan Nazish Naseer Muhammad Ashhad Ullah Khalil |
| author_sort | Muhammad Abdul Mabood Khalil |
| collection | DOAJ |
| description | Ovarian hyperstimulation syndrome (OHSS) was first described in 1960. It may occur as a complication of gonadotropin hormone therapy during assisted pregnancy or for primary infertility. A 26-year-old female patient with polycystic ovarian syndrome and primary infertility was treated to conceive. She received intravenous gonadotropin-releasing hormone (GnRH) along with follicle-stimulating hormone in an outside private clinic. She presented to the emergency department with abdominal and chest pain, loose stool, vomiting, shortness of breath and decreasing urine output. She was found to have edema, ascites, effusion and acute kidney injury (AKI). Considering the symptoms preceding the drug history and anasarca, a diagnosis of severe OHSS was made. Ascites was further complicated by spontaneous bacterial peritonitis (SBP), which had already been reported before. We speculate that low immunity due to decreased immunoglobulin in patients with OHSS makes them prone to SBP. In our case, septicemia secondary to SBP and fluid loss due to capillary leakage from OHSS resulted in AKI and respiratory failure. This critically ill patient was treated in a special care unit, and she fully recovered with supportive measures. Severe OHSS may present as anasarca including ascites which can develop SBP leading to sepsis and multiorgan failure. |
| first_indexed | 2024-12-22T08:11:30Z |
| format | Article |
| id | doaj.art-674395249ee5433fa9c00fc3721f931d |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-22T08:11:30Z |
| publishDate | 2016-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-674395249ee5433fa9c00fc3721f931d2022-12-21T18:33:01ZengKarger PublishersCase Reports in Gastroenterology1662-06312016-08-0110242343010.1159/000446766446766Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney FailureMuhammad Abdul Mabood KhalilMuhammad Salman GhazniJackson TanNazish NaseerMuhammad Ashhad Ullah KhalilOvarian hyperstimulation syndrome (OHSS) was first described in 1960. It may occur as a complication of gonadotropin hormone therapy during assisted pregnancy or for primary infertility. A 26-year-old female patient with polycystic ovarian syndrome and primary infertility was treated to conceive. She received intravenous gonadotropin-releasing hormone (GnRH) along with follicle-stimulating hormone in an outside private clinic. She presented to the emergency department with abdominal and chest pain, loose stool, vomiting, shortness of breath and decreasing urine output. She was found to have edema, ascites, effusion and acute kidney injury (AKI). Considering the symptoms preceding the drug history and anasarca, a diagnosis of severe OHSS was made. Ascites was further complicated by spontaneous bacterial peritonitis (SBP), which had already been reported before. We speculate that low immunity due to decreased immunoglobulin in patients with OHSS makes them prone to SBP. In our case, septicemia secondary to SBP and fluid loss due to capillary leakage from OHSS resulted in AKI and respiratory failure. This critically ill patient was treated in a special care unit, and she fully recovered with supportive measures. Severe OHSS may present as anasarca including ascites which can develop SBP leading to sepsis and multiorgan failure.http://www.karger.com/Article/FullText/446766Spontaneous bacterial peritonitisOvarian hyperstimulation syndromeAcute kidney injury |
| spellingShingle | Muhammad Abdul Mabood Khalil Muhammad Salman Ghazni Jackson Tan Nazish Naseer Muhammad Ashhad Ullah Khalil Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure Case Reports in Gastroenterology Spontaneous bacterial peritonitis Ovarian hyperstimulation syndrome Acute kidney injury |
| title | Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure |
| title_full | Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure |
| title_fullStr | Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure |
| title_full_unstemmed | Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure |
| title_short | Spontaneous Bacterial Peritonitis and Anasarca in a Female Patient with Ovarian Hyperstimulation Syndrome Complicated by Respiratory and Kidney Failure |
| title_sort | spontaneous bacterial peritonitis and anasarca in a female patient with ovarian hyperstimulation syndrome complicated by respiratory and kidney failure |
| topic | Spontaneous bacterial peritonitis Ovarian hyperstimulation syndrome Acute kidney injury |
| url | http://www.karger.com/Article/FullText/446766 |
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