Much Ado About the New Definitions of Sepsis

Following the publication of the new definition of sepsis (Sepsis-3), a plethora of articles have been published in medical journals. Recognizing the epidemiological importance of the previous definitions, first issued in 1992 (Sepsis-1), and subsequently revised in 2001 (Sepsis-2), the most recent...

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Main Authors: Copotoiu Sanda-Maria, Copotoiu Ruxandra
Format: Article
Language:English
Published: Sciendo 2016-04-01
Series:The Journal of Critical Care Medicine
Subjects:
Online Access:https://doi.org/10.1515/jccm-2016-0015
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author Copotoiu Sanda-Maria
Copotoiu Ruxandra
author_facet Copotoiu Sanda-Maria
Copotoiu Ruxandra
author_sort Copotoiu Sanda-Maria
collection DOAJ
description Following the publication of the new definition of sepsis (Sepsis-3), a plethora of articles have been published in medical journals. Recognizing the epidemiological importance of the previous definitions, first issued in 1992 (Sepsis-1), and subsequently revised in 2001 (Sepsis-2), the most recent opinion emphasizes the failure “to provide adequate groups of patients with homogenous aetiologies, presentations and outcomes”, and blamed one of the causes “for the failure of several randomized controlled trials (RCTs), that tested the efficacy of adjuvant sepsis therapies”. This review summarizes the recent advances in sepsis definition.
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spelling doaj.art-674c83b4b20646efbcd5e951c292ee9d2023-12-02T05:48:24ZengSciendoThe Journal of Critical Care Medicine2393-18172016-04-0122677210.1515/jccm-2016-0015jccm-2016-0015Much Ado About the New Definitions of SepsisCopotoiu Sanda-Maria0Copotoiu Ruxandra1 University of Medicine and Pharmacy of Tirgu Mures, Romania, Clinic of Anesthesia and Intensive Care Emergency County Hospital of Tîrgu Mures, Gheorghe Marinescu street no 38, Tirgu Mures, Romania Les Hôpitaux Universitaires de Strasbourg, Pôle d’anesthésie - réanimations chirurgicales - SAMU - SMUR, Service d’anesthésiologie, Hôpital CivilFollowing the publication of the new definition of sepsis (Sepsis-3), a plethora of articles have been published in medical journals. Recognizing the epidemiological importance of the previous definitions, first issued in 1992 (Sepsis-1), and subsequently revised in 2001 (Sepsis-2), the most recent opinion emphasizes the failure “to provide adequate groups of patients with homogenous aetiologies, presentations and outcomes”, and blamed one of the causes “for the failure of several randomized controlled trials (RCTs), that tested the efficacy of adjuvant sepsis therapies”. This review summarizes the recent advances in sepsis definition.https://doi.org/10.1515/jccm-2016-0015sepsis definitionsepsis-3
spellingShingle Copotoiu Sanda-Maria
Copotoiu Ruxandra
Much Ado About the New Definitions of Sepsis
The Journal of Critical Care Medicine
sepsis definition
sepsis-3
title Much Ado About the New Definitions of Sepsis
title_full Much Ado About the New Definitions of Sepsis
title_fullStr Much Ado About the New Definitions of Sepsis
title_full_unstemmed Much Ado About the New Definitions of Sepsis
title_short Much Ado About the New Definitions of Sepsis
title_sort much ado about the new definitions of sepsis
topic sepsis definition
sepsis-3
url https://doi.org/10.1515/jccm-2016-0015
work_keys_str_mv AT copotoiusandamaria muchadoaboutthenewdefinitionsofsepsis
AT copotoiuruxandra muchadoaboutthenewdefinitionsofsepsis