A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine
In the present work, we prepared a simple and novel electrochemical sensor based on zeolitic imidazolate framework-67 (ZIF-67) and ionic liquid 1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF6) modified carbon paste electrode (CPE), which was effectively used for the determination of N-ac...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2023-11-01
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| Series: | Journal of Electrochemical Science and Engineering |
| Subjects: | |
| Online Access: | https://pub.iapchem.org/ojs/index.php/JESE/article/view/2039 |
| _version_ | 1797399218899386368 |
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| author | Somayeh Tajik Peyman Mohammadzadeh Jahani Fariba Garkani |
| author_facet | Somayeh Tajik Peyman Mohammadzadeh Jahani Fariba Garkani |
| author_sort | Somayeh Tajik |
| collection | DOAJ |
| description |
In the present work, we prepared a simple and novel electrochemical sensor based on zeolitic imidazolate framework-67 (ZIF-67) and ionic liquid 1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF6) modified carbon paste electrode (CPE), which was effectively used for the determination of N-acetylcysteine. The cyclic voltammetry studies demonstrated the lowest peak potential and the enhanced peak current response for N-acetylcysteine at the surface of ZIF-67/BMIM.PF6-modified CPE compared to the other CPEs due to the significant catalytic effect of ZIF-67 and BMIM.PF6, as well as the combination of them. Under the optimized conditions, the electrochemical response of ZIF-67/BMIM.PF6/CPE sensor provided a good linear relationship with N-acetylcysteine concentration from 0.04 to 435.0 µM. The limit of detection is estimated to be 0.01 μM for N-acetylcysteine. In further studies and measurements, the estimation of N-acetylcysteine in tablet samples confirms the usefulness of the ZIF-67/BMIM.PF6/CPE sensor.
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| first_indexed | 2024-03-09T01:37:10Z |
| format | Article |
| id | doaj.art-674ec596ce924fdbbf1213bea0c6decc |
| institution | Directory Open Access Journal |
| issn | 1847-9286 |
| language | English |
| last_indexed | 2024-03-09T01:37:10Z |
| publishDate | 2023-11-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | Journal of Electrochemical Science and Engineering |
| spelling | doaj.art-674ec596ce924fdbbf1213bea0c6decc2023-12-09T01:24:11ZengInternational Association of Physical Chemists (IAPC)Journal of Electrochemical Science and Engineering1847-92862023-11-0110.5599/jese.2039A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine Somayeh Tajik0Peyman Mohammadzadeh Jahani1Fariba Garkani2NanoBioelectrochemistry Research Center, Bam University of Medical Sciences, Bam, IranSchool of Medicine, Bam University of Medical Sciences, Bam, IranResearch Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran In the present work, we prepared a simple and novel electrochemical sensor based on zeolitic imidazolate framework-67 (ZIF-67) and ionic liquid 1-Butyl-3-methylimidazolium hexafluorophosphate (BMIM.PF6) modified carbon paste electrode (CPE), which was effectively used for the determination of N-acetylcysteine. The cyclic voltammetry studies demonstrated the lowest peak potential and the enhanced peak current response for N-acetylcysteine at the surface of ZIF-67/BMIM.PF6-modified CPE compared to the other CPEs due to the significant catalytic effect of ZIF-67 and BMIM.PF6, as well as the combination of them. Under the optimized conditions, the electrochemical response of ZIF-67/BMIM.PF6/CPE sensor provided a good linear relationship with N-acetylcysteine concentration from 0.04 to 435.0 µM. The limit of detection is estimated to be 0.01 μM for N-acetylcysteine. In further studies and measurements, the estimation of N-acetylcysteine in tablet samples confirms the usefulness of the ZIF-67/BMIM.PF6/CPE sensor. https://pub.iapchem.org/ojs/index.php/JESE/article/view/2039Zeolitic imidazolate framework-67Ionic liquidcarbon paste electrodemetal-organic frameworknanomaterials |
| spellingShingle | Somayeh Tajik Peyman Mohammadzadeh Jahani Fariba Garkani A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine Journal of Electrochemical Science and Engineering Zeolitic imidazolate framework-67 Ionic liquid carbon paste electrode metal-organic framework nanomaterials |
| title | A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine |
| title_full | A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine |
| title_fullStr | A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine |
| title_full_unstemmed | A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine |
| title_short | A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine |
| title_sort | simple sensitive and cost effective electrochemical sensor for the determination of n acetylcysteine |
| topic | Zeolitic imidazolate framework-67 Ionic liquid carbon paste electrode metal-organic framework nanomaterials |
| url | https://pub.iapchem.org/ojs/index.php/JESE/article/view/2039 |
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