Adverse Drug Reactions in Mazandaran Province, Iran, 2004-2018
Background and purpose: Adverse drug reaction (ADR) is one of the major causes of mortality and morbidity in patients that results in high healthcare costs. This study was conducted in Food and Drug Deputy at Mazandaran University to evaluate ADRs in Mazandaran province. Materials and methods: The a...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2020-05-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-14541-en.html |
| _version_ | 1797944073296805888 |
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| author | Fatemeh Izadpanah Mina Amini Atefeh Asadollahpour Zeinab Esfahani Majid Yousofi |
| author_facet | Fatemeh Izadpanah Mina Amini Atefeh Asadollahpour Zeinab Esfahani Majid Yousofi |
| author_sort | Fatemeh Izadpanah |
| collection | DOAJ |
| description | Background and purpose: Adverse drug reaction (ADR) is one of the major causes of mortality and morbidity in patients that results in high healthcare costs. This study was conducted in Food and Drug Deputy at Mazandaran University to evaluate ADRs in Mazandaran province.
Materials and methods: The analysis was performed during 2004-2018, based on the frequency of the drugs that had side effects, routes of administration, the number of reports per year, patient characteristics (gender, age), the frequency of the organ damaged, and the reporter.
Results: A total of 4425 reports of ADRs were submitted to Adverse Drug Reactions Center in Food and Drug Department, Mazandaran province, Iran. More than half of the reports (61%) were reported by nurses and 58.4% of the ADRs occurred in women. Injectable drugs were found with more adverse effects (75.7%) and the most prevalent were skin and hair disorders (50.6%). Anti-infective agents were the top drugs that caused ADRs (52.2%) and ceftriaxone was the most prevalent.
Conclusion: Due to the low number of ADRs in Mazandaran province and its low concordance with international standards, it seems that trainings based on the needs and preferences of medical groups about pharmacovigilance and focuses on how to report, can increase their awareness and knowledge about ADR and bring the data closer to world standards. |
| first_indexed | 2024-04-10T20:33:52Z |
| format | Article |
| id | doaj.art-67502b55bd83443d9c706b5ae0e75018 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:33:52Z |
| publishDate | 2020-05-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-67502b55bd83443d9c706b5ae0e750182023-01-25T05:01:54ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792020-05-013018596103Adverse Drug Reactions in Mazandaran Province, Iran, 2004-2018Fatemeh Izadpanah0Mina Amini1Atefeh Asadollahpour2Zeinab Esfahani3Majid Yousofi4 Assistant Professor of Clinical Pharmacy, Food and Drug Administration of Iran, Ministry of Health and Medical Education, Tehran, Iran Doctor of Pharmacy, Food and Drug Deputy, Mazandaran University of Medical Sciences, Sari, Iran The Health of Plant and Livestock Products Research Center, Mazandaran University of Medical Sciences, Sari, Iran Doctor of Pharmacy, Food and Drug Deputy, Mazandaran University of Medical Sciences, Sari, Iran Doctor of Pharmacy, Food and Drug Deputy, Mazandaran University of Medical Sciences, Sari, Iran Doctor of Pharmacy, Food and Drug Deputy, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Adverse drug reaction (ADR) is one of the major causes of mortality and morbidity in patients that results in high healthcare costs. This study was conducted in Food and Drug Deputy at Mazandaran University to evaluate ADRs in Mazandaran province. Materials and methods: The analysis was performed during 2004-2018, based on the frequency of the drugs that had side effects, routes of administration, the number of reports per year, patient characteristics (gender, age), the frequency of the organ damaged, and the reporter. Results: A total of 4425 reports of ADRs were submitted to Adverse Drug Reactions Center in Food and Drug Department, Mazandaran province, Iran. More than half of the reports (61%) were reported by nurses and 58.4% of the ADRs occurred in women. Injectable drugs were found with more adverse effects (75.7%) and the most prevalent were skin and hair disorders (50.6%). Anti-infective agents were the top drugs that caused ADRs (52.2%) and ceftriaxone was the most prevalent. Conclusion: Due to the low number of ADRs in Mazandaran province and its low concordance with international standards, it seems that trainings based on the needs and preferences of medical groups about pharmacovigilance and focuses on how to report, can increase their awareness and knowledge about ADR and bring the data closer to world standards.http://jmums.mazums.ac.ir/article-1-14541-en.htmlpharmacovigilanceadverse drug reactionyellow card |
| spellingShingle | Fatemeh Izadpanah Mina Amini Atefeh Asadollahpour Zeinab Esfahani Majid Yousofi Adverse Drug Reactions in Mazandaran Province, Iran, 2004-2018 Journal of Mazandaran University of Medical Sciences pharmacovigilance adverse drug reaction yellow card |
| title | Adverse Drug Reactions in Mazandaran Province,
Iran, 2004-2018 |
| title_full | Adverse Drug Reactions in Mazandaran Province,
Iran, 2004-2018 |
| title_fullStr | Adverse Drug Reactions in Mazandaran Province,
Iran, 2004-2018 |
| title_full_unstemmed | Adverse Drug Reactions in Mazandaran Province,
Iran, 2004-2018 |
| title_short | Adverse Drug Reactions in Mazandaran Province,
Iran, 2004-2018 |
| title_sort | adverse drug reactions in mazandaran province iran 2004 2018 |
| topic | pharmacovigilance adverse drug reaction yellow card |
| url | http://jmums.mazums.ac.ir/article-1-14541-en.html |
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