Cryo-EM structures of African swine fever virus topoisomerase

ABSTRACT Type II topoisomerases ubiquitously exist in cellular organisms, where they play an essential role in resolving the topological problems of DNA. The viral type II topoisomerase encoded by the African swine fever virus (ASFV) is critical for viral replication and infection, thus representing...

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Bibliographic Details
Main Authors: Yan Zhao, Wenhua Kuang, Qiyin An, Jinyue Li, Yong Wang, Zengqin Deng
Format: Article
Language:English
Published: American Society for Microbiology 2023-10-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01228-23