Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan
Background: Various systemic diseases can cause oral manifestations, such as inflammatory bowel disease (IBD). This study is designed to investigate the frequency of oral manifestations in patients with IBD referred to health centers and offices in Isfahan in 2018. Materials and Methods: This cross-...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Dental Research Journal |
| Subjects: | |
| Online Access: | http://www.drjjournal.net/article.asp?issn=1735-3327;year=2021;volume=18;issue=1;spage=4;epage=4;aulast=Khozeimeh |
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| author | Faezeh Khozeimeh Hadi Shakerin Hamed Daghaghzadeh Fereshteh Najarzadegan Zahra Golestannejad Peyman Adibi |
| author_facet | Faezeh Khozeimeh Hadi Shakerin Hamed Daghaghzadeh Fereshteh Najarzadegan Zahra Golestannejad Peyman Adibi |
| author_sort | Faezeh Khozeimeh |
| collection | DOAJ |
| description | Background: Various systemic diseases can cause oral manifestations, such as inflammatory bowel disease (IBD). This study is designed to investigate the frequency of oral manifestations in patients with IBD referred to health centers and offices in Isfahan in 2018.
Materials and Methods: This cross-sectional study was done among 161 patients suffering from IBD in Isfahan, Iran. They were chosen by the systematic randomized sampling. Finally, the data were analyzed using the logistic regression test in the SPSS software. Significance was assigned at P < 0.05.
Results: The number of patients with ulcerative colitis and Crohn's syndrome was, respectively, 119 persons (73.9%) and 42 persons (26.1%). Oral manifestations were seen among 52 (32.3%) of the samples. The frequency of oral manifestations was 35.6% (31 cases) in males and 28.4% (21 cases) in females. Oral manifestations were seen in 29.4% of patients with ulcerative colitis and 40.5% of patients with Crohn's disease. Based on the logistic regression, there was a statistically significant relationship between the use of azathioprine and mesalazine with oral manifestations (P < 0.05), whereas the severity of disease and smoking were not statistically significantly related to oral manifestations (P > 0.05).
Conclusion: The severity of the disease was not significantly correlated with oral manifestations, which are in agreement with the results of previous studies. It was also found that among patients with IBD, the oral aphthous ulcers can appear 1–3 years before the diagnosis of the disease. Besides that, some of the drugs used to treat the disease have a significant relationship with oral manifestations. |
| first_indexed | 2024-12-20T03:31:42Z |
| format | Article |
| id | doaj.art-67528687629a432cbf346b8f2b6c5404 |
| institution | Directory Open Access Journal |
| issn | 1735-3327 2008-0255 |
| language | English |
| last_indexed | 2024-12-20T03:31:42Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Dental Research Journal |
| spelling | doaj.art-67528687629a432cbf346b8f2b6c54042022-12-21T19:54:58ZengWolters Kluwer Medknow PublicationsDental Research Journal1735-33272008-02552021-01-011814410.4103/1735-3327.310033Oral manifestations in inflammatory bowel disease: A cross-sectional study in IsfahanFaezeh KhozeimehHadi ShakerinHamed DaghaghzadehFereshteh NajarzadeganZahra GolestannejadPeyman AdibiBackground: Various systemic diseases can cause oral manifestations, such as inflammatory bowel disease (IBD). This study is designed to investigate the frequency of oral manifestations in patients with IBD referred to health centers and offices in Isfahan in 2018. Materials and Methods: This cross-sectional study was done among 161 patients suffering from IBD in Isfahan, Iran. They were chosen by the systematic randomized sampling. Finally, the data were analyzed using the logistic regression test in the SPSS software. Significance was assigned at P < 0.05. Results: The number of patients with ulcerative colitis and Crohn's syndrome was, respectively, 119 persons (73.9%) and 42 persons (26.1%). Oral manifestations were seen among 52 (32.3%) of the samples. The frequency of oral manifestations was 35.6% (31 cases) in males and 28.4% (21 cases) in females. Oral manifestations were seen in 29.4% of patients with ulcerative colitis and 40.5% of patients with Crohn's disease. Based on the logistic regression, there was a statistically significant relationship between the use of azathioprine and mesalazine with oral manifestations (P < 0.05), whereas the severity of disease and smoking were not statistically significantly related to oral manifestations (P > 0.05). Conclusion: The severity of the disease was not significantly correlated with oral manifestations, which are in agreement with the results of previous studies. It was also found that among patients with IBD, the oral aphthous ulcers can appear 1–3 years before the diagnosis of the disease. Besides that, some of the drugs used to treat the disease have a significant relationship with oral manifestations.http://www.drjjournal.net/article.asp?issn=1735-3327;year=2021;volume=18;issue=1;spage=4;epage=4;aulast=Khozeimehcolitiscrohn diseaseinflammatory bowel diseaseoral manifestationsulcerative |
| spellingShingle | Faezeh Khozeimeh Hadi Shakerin Hamed Daghaghzadeh Fereshteh Najarzadegan Zahra Golestannejad Peyman Adibi Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan Dental Research Journal colitis crohn disease inflammatory bowel disease oral manifestations ulcerative |
| title | Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan |
| title_full | Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan |
| title_fullStr | Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan |
| title_full_unstemmed | Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan |
| title_short | Oral manifestations in inflammatory bowel disease: A cross-sectional study in Isfahan |
| title_sort | oral manifestations in inflammatory bowel disease a cross sectional study in isfahan |
| topic | colitis crohn disease inflammatory bowel disease oral manifestations ulcerative |
| url | http://www.drjjournal.net/article.asp?issn=1735-3327;year=2021;volume=18;issue=1;spage=4;epage=4;aulast=Khozeimeh |
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