A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population
Aim: To evaluate the association of serum alkaline phosphatase (ALP) and calcium level in type 2 diabetes mellitus with periodontitis. Materials and Methods: In this study, a total of 240 subjects, aged 34-42 years were selected and was divided into four groups as 60 healthy individuals (group A), 6...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | SRM Journal of Research in Dental Sciences |
| Subjects: | |
| Online Access: | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2012;volume=3;issue=3;spage=175;epage=179;aulast=Pushpa |
| _version_ | 1811196514871017472 |
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| author | D S Pushpa Rani S Nirmala Anandan |
| author_facet | D S Pushpa Rani S Nirmala Anandan |
| author_sort | D S Pushpa Rani |
| collection | DOAJ |
| description | Aim: To evaluate the association of serum alkaline phosphatase (ALP) and calcium level in type 2 diabetes mellitus with periodontitis. Materials and Methods: In this study, a total of 240 subjects, aged 34-42 years were selected and was divided into four groups as 60 healthy individuals (group A), 60 type 2 diabetes mellitus without periodontitis (group B), 60 type 2 diabetes mellitus with periodontitis (group C), and 60 non-diabetes mellitus with periodontitis (group D). Blood samples were collected after an overnight fast for the estimation of serum glucose, ALP, and calcium using glucose oxidase-peroxidase (GOD-POD), p-Nitrophenyl Phosphate (p-NPP), and o-Cresolphthalein Complexone (OCPC) methods, respectively. Results: The concentration of serum ALP and calcium showed a significant increase ( P < 0.0001) in type 2 diabetes mellitus patients with periodontitis (group C) when compared to control. Conclusion: Increased serum ALP and calcium level could be often associated with the alveolar bone loss and tooth loss in type 2 diabetes mellitus with periodontitis among the South Indian population. |
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| format | Article |
| id | doaj.art-675d6c56900a44409b2d66672aaa8ab3 |
| institution | Directory Open Access Journal |
| issn | 2772-5243 2772-5251 |
| language | English |
| last_indexed | 2024-04-12T01:00:05Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | SRM Journal of Research in Dental Sciences |
| spelling | doaj.art-675d6c56900a44409b2d66672aaa8ab32022-12-22T03:54:30ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512012-01-013317517910.4103/0976-433X.107396A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian populationD S Pushpa RaniS Nirmala AnandanAim: To evaluate the association of serum alkaline phosphatase (ALP) and calcium level in type 2 diabetes mellitus with periodontitis. Materials and Methods: In this study, a total of 240 subjects, aged 34-42 years were selected and was divided into four groups as 60 healthy individuals (group A), 60 type 2 diabetes mellitus without periodontitis (group B), 60 type 2 diabetes mellitus with periodontitis (group C), and 60 non-diabetes mellitus with periodontitis (group D). Blood samples were collected after an overnight fast for the estimation of serum glucose, ALP, and calcium using glucose oxidase-peroxidase (GOD-POD), p-Nitrophenyl Phosphate (p-NPP), and o-Cresolphthalein Complexone (OCPC) methods, respectively. Results: The concentration of serum ALP and calcium showed a significant increase ( P < 0.0001) in type 2 diabetes mellitus patients with periodontitis (group C) when compared to control. Conclusion: Increased serum ALP and calcium level could be often associated with the alveolar bone loss and tooth loss in type 2 diabetes mellitus with periodontitis among the South Indian population.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2012;volume=3;issue=3;spage=175;epage=179;aulast=Pushpaalkaline phosphatasealveolar bone losscalciumperiodontitistype 2 diabetes mellitus |
| spellingShingle | D S Pushpa Rani S Nirmala Anandan A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population SRM Journal of Research in Dental Sciences alkaline phosphatase alveolar bone loss calcium periodontitis type 2 diabetes mellitus |
| title | A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population |
| title_full | A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population |
| title_fullStr | A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population |
| title_full_unstemmed | A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population |
| title_short | A clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south Indian population |
| title_sort | clinical study of serum alkaline phosphatase and calcium level in type 2 diabetes mellitus with periodontitis among the south indian population |
| topic | alkaline phosphatase alveolar bone loss calcium periodontitis type 2 diabetes mellitus |
| url | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2012;volume=3;issue=3;spage=175;epage=179;aulast=Pushpa |
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