Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and carotenoids . Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as mod...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
College of Medicine University of Baghdad
2007-01-01
|
Series: | مجلة كلية الطب |
Subjects: | |
Online Access: | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475 |
_version_ | 1797368655416131584 |
---|---|
author | Hayder Ali Mohammed Ghassan A. Al-Shamma Hashim M. Hashim |
author_facet | Hayder Ali Mohammed Ghassan A. Al-Shamma Hashim M. Hashim |
author_sort | Hayder Ali Mohammed |
collection | DOAJ |
description | Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and
carotenoids .
Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as modulated by glycemic control and oxidative stress .
Subjects & methods : Multiple biochemical parameters were obtained from plasma of 57 patients with type 2 diabetes mellitus ( 25 males and 32 females ) , on oral hypoglycemic with
a disease duration of 1- 15 years and 37 healthy normal subject s of matching age and sex to serve as controls. The biochemical parameters measured in the present study included the glycated Hb (HbA1c ), serum lipids ( total cholesterol TC, triglycerides TG , high and low density lipoprotein cholesterols , HDL-C & LDL-C ) , lipid peroxides and serum ß-carotene.
results revealed a marked reduction of ß- carotene in the diabetics in a pattern proportional to that of the glycemic control ,dyslipidemia and oxidative stress .
Possible causes , mechanisms and suggestions underlining these changes are discussed. |
first_indexed | 2024-03-08T17:35:52Z |
format | Article |
id | doaj.art-675dcb02bc024451a1d90655abc07717 |
institution | Directory Open Access Journal |
issn | 0041-9419 2410-8057 |
language | English |
last_indexed | 2024-03-08T17:35:52Z |
publishDate | 2007-01-01 |
publisher | College of Medicine University of Baghdad |
record_format | Article |
series | مجلة كلية الطب |
spelling | doaj.art-675dcb02bc024451a1d90655abc077172024-01-02T12:45:35ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-01-01484Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes MellitusHayder Ali Mohammed0Ghassan A. Al-Shamma1Hashim M. Hashim2department of physiological chemistry,department of physiological chemistryDepartment of medicine , College of Medicine, Al-Nahrain University, Baghdad.Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and carotenoids . Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as modulated by glycemic control and oxidative stress . Subjects & methods : Multiple biochemical parameters were obtained from plasma of 57 patients with type 2 diabetes mellitus ( 25 males and 32 females ) , on oral hypoglycemic with a disease duration of 1- 15 years and 37 healthy normal subject s of matching age and sex to serve as controls. The biochemical parameters measured in the present study included the glycated Hb (HbA1c ), serum lipids ( total cholesterol TC, triglycerides TG , high and low density lipoprotein cholesterols , HDL-C & LDL-C ) , lipid peroxides and serum ß-carotene. results revealed a marked reduction of ß- carotene in the diabetics in a pattern proportional to that of the glycemic control ,dyslipidemia and oxidative stress . Possible causes , mechanisms and suggestions underlining these changes are discussed.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins . |
spellingShingle | Hayder Ali Mohammed Ghassan A. Al-Shamma Hashim M. Hashim Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus مجلة كلية الطب ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins . |
title | Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus |
title_full | Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus |
title_fullStr | Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus |
title_full_unstemmed | Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus |
title_short | Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus |
title_sort | beta carotene glycemic control and dyslipidemia in type 2 diabetes mellitus |
topic | ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins . |
url | http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475 |
work_keys_str_mv | AT hayderalimohammed betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus AT ghassanaalshamma betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus AT hashimmhashim betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus |