Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus

Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and carotenoids .  Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as mod...

Full description

Bibliographic Details
Main Authors: Hayder Ali Mohammed, Ghassan A. Al-Shamma, Hashim M. Hashim
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2007-01-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475
_version_ 1797368655416131584
author Hayder Ali Mohammed
Ghassan A. Al-Shamma
Hashim M. Hashim
author_facet Hayder Ali Mohammed
Ghassan A. Al-Shamma
Hashim M. Hashim
author_sort Hayder Ali Mohammed
collection DOAJ
description Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and carotenoids .  Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as modulated by glycemic control and oxidative stress . Subjects & methods : Multiple biochemical parameters were obtained from plasma of 57 patients with type 2 diabetes mellitus ( 25 males and 32 females ) , on oral hypoglycemic with a disease duration of 1- 15 years and 37 healthy normal subject s of matching age and sex to serve as controls. The biochemical parameters measured in the present study included the glycated Hb (HbA1c ), serum lipids ( total cholesterol TC, triglycerides TG , high and low density lipoprotein cholesterols , HDL-C & LDL-C ) , lipid peroxides and serum ß-carotene. results revealed a marked reduction of ß- carotene in the diabetics in a pattern proportional to that of the glycemic control ,dyslipidemia and oxidative stress . Possible causes , mechanisms and suggestions underlining these changes are discussed.
first_indexed 2024-03-08T17:35:52Z
format Article
id doaj.art-675dcb02bc024451a1d90655abc07717
institution Directory Open Access Journal
issn 0041-9419
2410-8057
language English
last_indexed 2024-03-08T17:35:52Z
publishDate 2007-01-01
publisher College of Medicine University of Baghdad
record_format Article
series مجلة كلية الطب
spelling doaj.art-675dcb02bc024451a1d90655abc077172024-01-02T12:45:35ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572007-01-01484Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes MellitusHayder Ali Mohammed0Ghassan A. Al-Shamma1Hashim M. Hashim2department of physiological chemistry,department of physiological chemistryDepartment of medicine , College of Medicine, Al-Nahrain University, Baghdad.Background : Diabetes mellitus is a stressful condition in which the increased production of free radicals impairs the generation of naturally occurring antioxidants like vitamins and carotenoids .  Aim :The present study deals with the changes in serum ß-carotene in type 2 diabetes mellitus, as modulated by glycemic control and oxidative stress . Subjects & methods : Multiple biochemical parameters were obtained from plasma of 57 patients with type 2 diabetes mellitus ( 25 males and 32 females ) , on oral hypoglycemic with a disease duration of 1- 15 years and 37 healthy normal subject s of matching age and sex to serve as controls. The biochemical parameters measured in the present study included the glycated Hb (HbA1c ), serum lipids ( total cholesterol TC, triglycerides TG , high and low density lipoprotein cholesterols , HDL-C & LDL-C ) , lipid peroxides and serum ß-carotene. results revealed a marked reduction of ß- carotene in the diabetics in a pattern proportional to that of the glycemic control ,dyslipidemia and oxidative stress . Possible causes , mechanisms and suggestions underlining these changes are discussed.http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins .
spellingShingle Hayder Ali Mohammed
Ghassan A. Al-Shamma
Hashim M. Hashim
Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
مجلة كلية الطب
ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins .
title Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
title_full Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
title_fullStr Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
title_full_unstemmed Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
title_short Beta-Carotene, Glycemic Control And Dyslipidemia In Type 2 Diabetes Mellitus
title_sort beta carotene glycemic control and dyslipidemia in type 2 diabetes mellitus
topic ß –carotene , diabetes mellitus , oxidative stress ,Oxidized Lipoproteins .
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1475
work_keys_str_mv AT hayderalimohammed betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus
AT ghassanaalshamma betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus
AT hashimmhashim betacaroteneglycemiccontrolanddyslipidemiaintype2diabetesmellitus