Involvement of the GABAergic system in PTSD and its therapeutic significance

Involvement of the GABAergic system in PTSD and its therapeutic significance

The neurobiological mechanism of post-traumatic stress disorder (PTSD) is poorly understood. The inhibition of GABA neurons, especially in the amygdala, is crucial for the precise regulation of the consolidation, expression, and extinction of fear conditioning. The GABAergic system is involved in th...

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Bibliographic Details
Main Authors: Junhui Huang, Fei Xu, Liping Yang, Lina Tuolihong, Xiaoyu Wang, Zibo Du, Yiqi Zhang, Xuanlin Yin, Yingjun Li, Kangrong Lu, Wanshan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
post-traumatic stress disorder
GABA
fear memory
amygdala
neurotransmitter
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1052288/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1052288/full

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