The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis

<p><em>Pneumococcal infection remains the key cause of severe diseases of lower airways and deaths in children. The objective: to study the role of pneumococcal infection in pathogenesis of exacerbations of recurrent obstructive pulmonary diseases. Methods: etiological structure of lower...

Full description

Bibliographic Details
Main Authors: N.V. Kukhtinova, S.M. Gavalov, S.A. Krotov, V.A. Krotova
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2011-01-01
Series:Вопросы современной педиатрии
Online Access:http://vsp.spr-journal.ru:80/jour/article/view/563
_version_ 1797759528088895488
author N.V. Kukhtinova
S.M. Gavalov
S.A. Krotov
V.A. Krotova
author_facet N.V. Kukhtinova
S.M. Gavalov
S.A. Krotov
V.A. Krotova
author_sort N.V. Kukhtinova
collection DOAJ
description <p><em>Pneumococcal infection remains the key cause of severe diseases of lower airways and deaths in children. The objective: to study the role of pneumococcal infection in pathogenesis of exacerbations of recurrent obstructive pulmonary diseases. Methods: etiological structure of lower airways infections was evaluated in 125 patients 1–15 years old with bronchial asthma or recurrent bronchitis. Results: etiologic role of Streptococcus pneumoniae in development of low airways infections was detected in 48% of patients with atopic asthma, 85% — with asthma without atopy, 97% — with recurrent bronchitis. Repeated microbiological examination confirmed chronic carriage of S. рneumoniae in nasopharinx in 31% of patients. Conclusion: early active prophylaxis with vaccine against pneumococcal infection including conjugated vaccines is able to prevent further progression of a disease.</em></p><p><br /><strong><em>Key words: children, bronchial asthma, obstructive bronchitis, exacerbation, pneumococcal infection.</em></strong></p>
first_indexed 2024-03-12T18:45:42Z
format Article
id doaj.art-6765680d6f3b4306ae084aa966baa1bf
institution Directory Open Access Journal
issn 1682-5527
1682-5535
language English
last_indexed 2024-03-12T18:45:42Z
publishDate 2011-01-01
publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj.art-6765680d6f3b4306ae084aa966baa1bf2023-08-02T07:40:57Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-01-011022227563The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitisN.V. Kukhtinova0S.M. Gavalov1S.A. Krotov2V.A. Krotova3Novosibirsk State Medical UniversityNovosibirsk State Medical UniversityCC Vector-Best, NovosibirskCC Vector-Best, Novosibirsk<p><em>Pneumococcal infection remains the key cause of severe diseases of lower airways and deaths in children. The objective: to study the role of pneumococcal infection in pathogenesis of exacerbations of recurrent obstructive pulmonary diseases. Methods: etiological structure of lower airways infections was evaluated in 125 patients 1–15 years old with bronchial asthma or recurrent bronchitis. Results: etiologic role of Streptococcus pneumoniae in development of low airways infections was detected in 48% of patients with atopic asthma, 85% — with asthma without atopy, 97% — with recurrent bronchitis. Repeated microbiological examination confirmed chronic carriage of S. рneumoniae in nasopharinx in 31% of patients. Conclusion: early active prophylaxis with vaccine against pneumococcal infection including conjugated vaccines is able to prevent further progression of a disease.</em></p><p><br /><strong><em>Key words: children, bronchial asthma, obstructive bronchitis, exacerbation, pneumococcal infection.</em></strong></p>http://vsp.spr-journal.ru:80/jour/article/view/563
spellingShingle N.V. Kukhtinova
S.M. Gavalov
S.A. Krotov
V.A. Krotova
The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
Вопросы современной педиатрии
title The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
title_full The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
title_fullStr The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
title_full_unstemmed The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
title_short The role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
title_sort role of pneumococcal infection in development of exacerbations in children with bronchial asthma and obstructive bronchitis
url http://vsp.spr-journal.ru:80/jour/article/view/563
work_keys_str_mv AT nvkukhtinova theroleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT smgavalov theroleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT sakrotov theroleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT vakrotova theroleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT nvkukhtinova roleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT smgavalov roleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT sakrotov roleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis
AT vakrotova roleofpneumococcalinfectionindevelopmentofexacerbationsinchildrenwithbronchialasthmaandobstructivebronchitis