Non-Association of Driver Alterations in PTEN with Differential Gene Expression and Gene Methylation in IDH1 Wildtype Glioblastomas

Non-Association of Driver Alterations in PTEN with Differential Gene Expression and Gene Methylation in IDH1 Wildtype Glioblastomas

During oncogenesis, alterations in driver genes called driver alterations (DAs) modulate the transcriptome, methylome and proteome through oncogenic signaling pathways. These modulatory effects of any DA may be analyzed by examining differentially expressed mRNAs (DEMs), differentially methylated ge...

Full description

Bibliographic Details
Main Authors: Mrinmay Kumar Mallik, Kaushik Majumdar, Shiraz Mujtaba
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Brain Sciences
Subjects:
PTEN
driver alterations
IDH1 wildtype glioblastoma
Cbioportal
transcriptome
methylome
Online Access:https://www.mdpi.com/2076-3425/13/2/186

Similar Items

Similar Items