The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis
Abstract Background and objective Cardiac rehabilitation (CR) has been demonstrated to improve outcomes in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). However, the optimal CR initiation time and duration remain to be determined. This study aimed to...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | https://doi.org/10.1186/s12872-023-03692-z |
| _version_ | 1797363664360046592 |
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| author | Peiyu Zhang Chaofeng Niu Lijing Zhang Haixia Lai Birong Liu Diyang Lv Rui Zhuang Yong Liu Di Xiao Liyong Ma Meng Li |
| author_facet | Peiyu Zhang Chaofeng Niu Lijing Zhang Haixia Lai Birong Liu Diyang Lv Rui Zhuang Yong Liu Di Xiao Liyong Ma Meng Li |
| author_sort | Peiyu Zhang |
| collection | DOAJ |
| description | Abstract Background and objective Cardiac rehabilitation (CR) has been demonstrated to improve outcomes in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). However, the optimal CR initiation time and duration remain to be determined. This study aimed to explore the impact of the time factors on the CR outcomes in AMI patients who received PCI by the method of meta-regression analysis. Methods We searched five databases (PubMed, Embase, Cochrane Library, Web of Science and Google scholar) up to October 31, 2023. Meta-regression analysis was utilized to explore the impact of the time factors on the effect sizes. Subgroups with more than 3 studies were used for meta-regression analysis. Results Our analysis included 16 studies and a total of 1810 patients. The meta-regression analysis revealed that the initiation time and duration of CR had no significant impact on the occurrence of arrhythmia, coronary artery restenosis and angina pectoris. The initiation time and duration of CR also had no significant impact on the changes in left ventricular ejection fraction (LVEF, starting time: estimate = 0.160, p = 0.130; intervention time: estimate = 0.017, p = 0.149), left ventricular end-diastolic volume (LVEDV, starting time: estimate = − 0.191, p = 0.732; intervention time: estimate = − 0.033, p = 0.160), left ventricular end-systolic volume (LVESV, starting time: estimate = − 0.301, p = 0.464; intervention time: estimate = 0.015, p = 0.368) and 6-minute walk test (6MWT, starting time: estimate = − 0.108, p = 0.467; intervention time: estimate = 0.019, p = 0.116). Conclusion Implementation of CR following PCI in patients with AMI is beneficial. However, in AMI patients, there is no significant difference in the improvement of CR outcomes based on different CR starting times within 1 month after PCI or different durations of the CR programs. It indicates that it is feasible for patients with AMI to commence CR within 1 month after PCI and continue long-term CR, but the time factors which impact CR are intricate and further clinical research is still needed to determine the optimal initiation time and duration of CR. |
| first_indexed | 2024-03-08T16:24:18Z |
| format | Article |
| id | doaj.art-676c32489f1c42b59299b0bbd7cfc6e1 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-03-08T16:24:18Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-676c32489f1c42b59299b0bbd7cfc6e12024-01-07T12:10:07ZengBMCBMC Cardiovascular Disorders1471-22612024-01-0124111210.1186/s12872-023-03692-zThe impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysisPeiyu Zhang0Chaofeng Niu1Lijing Zhang2Haixia Lai3Birong Liu4Diyang Lv5Rui Zhuang6Yong Liu7Di Xiao8Liyong Ma9Meng Li10Department of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongfang Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese MedicineAbstract Background and objective Cardiac rehabilitation (CR) has been demonstrated to improve outcomes in patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI). However, the optimal CR initiation time and duration remain to be determined. This study aimed to explore the impact of the time factors on the CR outcomes in AMI patients who received PCI by the method of meta-regression analysis. Methods We searched five databases (PubMed, Embase, Cochrane Library, Web of Science and Google scholar) up to October 31, 2023. Meta-regression analysis was utilized to explore the impact of the time factors on the effect sizes. Subgroups with more than 3 studies were used for meta-regression analysis. Results Our analysis included 16 studies and a total of 1810 patients. The meta-regression analysis revealed that the initiation time and duration of CR had no significant impact on the occurrence of arrhythmia, coronary artery restenosis and angina pectoris. The initiation time and duration of CR also had no significant impact on the changes in left ventricular ejection fraction (LVEF, starting time: estimate = 0.160, p = 0.130; intervention time: estimate = 0.017, p = 0.149), left ventricular end-diastolic volume (LVEDV, starting time: estimate = − 0.191, p = 0.732; intervention time: estimate = − 0.033, p = 0.160), left ventricular end-systolic volume (LVESV, starting time: estimate = − 0.301, p = 0.464; intervention time: estimate = 0.015, p = 0.368) and 6-minute walk test (6MWT, starting time: estimate = − 0.108, p = 0.467; intervention time: estimate = 0.019, p = 0.116). Conclusion Implementation of CR following PCI in patients with AMI is beneficial. However, in AMI patients, there is no significant difference in the improvement of CR outcomes based on different CR starting times within 1 month after PCI or different durations of the CR programs. It indicates that it is feasible for patients with AMI to commence CR within 1 month after PCI and continue long-term CR, but the time factors which impact CR are intricate and further clinical research is still needed to determine the optimal initiation time and duration of CR.https://doi.org/10.1186/s12872-023-03692-zCardiac rehabilitationTimeAcute myocardial infarctionPercutaneous coronary interventionMeta-analysis |
| spellingShingle | Peiyu Zhang Chaofeng Niu Lijing Zhang Haixia Lai Birong Liu Diyang Lv Rui Zhuang Yong Liu Di Xiao Liyong Ma Meng Li The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis BMC Cardiovascular Disorders Cardiac rehabilitation Time Acute myocardial infarction Percutaneous coronary intervention Meta-analysis |
| title | The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis |
| title_full | The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis |
| title_fullStr | The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis |
| title_full_unstemmed | The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis |
| title_short | The impact of the time factors on the exercise-based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention: a systematic review and meta-analysis |
| title_sort | impact of the time factors on the exercise based cardiac rehabilitation outcomes of the patients with acute myocardial infarction after percutaneous coronary intervention a systematic review and meta analysis |
| topic | Cardiac rehabilitation Time Acute myocardial infarction Percutaneous coronary intervention Meta-analysis |
| url | https://doi.org/10.1186/s12872-023-03692-z |
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