Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg
Objective: The role of dipping blood pressure pattern in normotensives is unclear. The study aims to search the circadian blood pressure rhythm and the clinical determinants related to reverse dipping pattern in a strictly selected, normotensive population. Methods: The study population was divided...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-10-01
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| Series: | Clinical and Experimental Hypertension |
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| Online Access: | http://dx.doi.org/10.1080/10641963.2021.1925685 |
| _version_ | 1797681298988335104 |
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| author | Ali Çoner Ertan Akbay Sinan Akıncı Gökhan Özyıldız Gültekin Gençtoy Haldun Müderrisoğlu |
| author_facet | Ali Çoner Ertan Akbay Sinan Akıncı Gökhan Özyıldız Gültekin Gençtoy Haldun Müderrisoğlu |
| author_sort | Ali Çoner |
| collection | DOAJ |
| description | Objective: The role of dipping blood pressure pattern in normotensives is unclear. The study aims to search the circadian blood pressure rhythm and the clinical determinants related to reverse dipping pattern in a strictly selected, normotensive population. Methods: The study population was divided into three groups depending on the nocturnal dipping pattern as dipping, non-dipping, and reverse dipping. Basal clinical characteristics, anthropometric measurements, and spot urine samples from the first-morning void were collected. Clinical determinants related to the presence of reverse dipping pattern were tested by the Multiple Binary Logistic Regression analysis. Results: A total of 233 participants were involved in the study population (median age 45 years [40–50]). Dipping pattern was detected in 55.4%, non-dipping pattern in 33.0%, and reverse dipping pattern in 11.6% of the study population. There was no difference between the groups in terms of basal clinical features. Albumin-to-creatinine ratio (ACR) (p < .001) and hs-CRP levels (p = .006) were also statistically significant across the groups. ACR (HR: 1.195, 95% CI: 1.067–1.338, p = .002) and hs-CRP (HR: 2.438, 95% CI: 1.023–5.808, p = .044) were found to be related to the presence of reverse dipping blood pressure pattern. Conclusions: The absence of nocturnal physiological dipping is seen at a remarkable rate in the normotensive Turkish population. ACR and hs-CRP are the clinical determinants related to the presence of reverse dipping blood pressure pattern. |
| first_indexed | 2024-03-11T23:42:57Z |
| format | Article |
| id | doaj.art-676cc9c67214451db2089e27b164a8a3 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:42:57Z |
| publishDate | 2021-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-676cc9c67214451db2089e27b164a8a32023-09-19T15:19:30ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062021-10-0143764765210.1080/10641963.2021.19256851925685Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHgAli Çoner0Ertan Akbay1Sinan Akıncı2Gökhan Özyıldız3Gültekin Gençtoy4Haldun Müderrisoğlu5Baskent University Hospital Alanya Application and Research CenterBaskent University Hospital Alanya Application and Research CenterBaskent University Hospital Alanya Application and Research CenterRecep Tayyip Erdogan University Training and Research HospitalBaskent University Hospital Alanya Application and Research CenterBaskent University Faculty of MedicineObjective: The role of dipping blood pressure pattern in normotensives is unclear. The study aims to search the circadian blood pressure rhythm and the clinical determinants related to reverse dipping pattern in a strictly selected, normotensive population. Methods: The study population was divided into three groups depending on the nocturnal dipping pattern as dipping, non-dipping, and reverse dipping. Basal clinical characteristics, anthropometric measurements, and spot urine samples from the first-morning void were collected. Clinical determinants related to the presence of reverse dipping pattern were tested by the Multiple Binary Logistic Regression analysis. Results: A total of 233 participants were involved in the study population (median age 45 years [40–50]). Dipping pattern was detected in 55.4%, non-dipping pattern in 33.0%, and reverse dipping pattern in 11.6% of the study population. There was no difference between the groups in terms of basal clinical features. Albumin-to-creatinine ratio (ACR) (p < .001) and hs-CRP levels (p = .006) were also statistically significant across the groups. ACR (HR: 1.195, 95% CI: 1.067–1.338, p = .002) and hs-CRP (HR: 2.438, 95% CI: 1.023–5.808, p = .044) were found to be related to the presence of reverse dipping blood pressure pattern. Conclusions: The absence of nocturnal physiological dipping is seen at a remarkable rate in the normotensive Turkish population. ACR and hs-CRP are the clinical determinants related to the presence of reverse dipping blood pressure pattern.http://dx.doi.org/10.1080/10641963.2021.1925685ambulatory blood pressure monitoringcircadian blood pressure rhythmnocturnal dipping patternreverse dipping blood pressuretarget organ damage |
| spellingShingle | Ali Çoner Ertan Akbay Sinan Akıncı Gökhan Özyıldız Gültekin Gençtoy Haldun Müderrisoğlu Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg Clinical and Experimental Hypertension ambulatory blood pressure monitoring circadian blood pressure rhythm nocturnal dipping pattern reverse dipping blood pressure target organ damage |
| title | Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg |
| title_full | Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg |
| title_fullStr | Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg |
| title_full_unstemmed | Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg |
| title_short | Determinants of reverse dipping blood pressure in normotensive, non-diabetic population with an office measurement below 130/85mmHg |
| title_sort | determinants of reverse dipping blood pressure in normotensive non diabetic population with an office measurement below 130 85mmhg |
| topic | ambulatory blood pressure monitoring circadian blood pressure rhythm nocturnal dipping pattern reverse dipping blood pressure target organ damage |
| url | http://dx.doi.org/10.1080/10641963.2021.1925685 |
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