Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia
Neonates who are born preterm frequently have inadequate lung development to support independent breathing and will need respiratory support. The underdeveloped lung is also particularly susceptible to lung injury, especially during the first weeks of life. Consequently, respiratory support strategi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1087857/full |
| _version_ | 1811161490887016448 |
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| author | Erik B. Hysinger Shawn K. Ahlfeld |
| author_facet | Erik B. Hysinger Shawn K. Ahlfeld |
| author_sort | Erik B. Hysinger |
| collection | DOAJ |
| description | Neonates who are born preterm frequently have inadequate lung development to support independent breathing and will need respiratory support. The underdeveloped lung is also particularly susceptible to lung injury, especially during the first weeks of life. Consequently, respiratory support strategies in the early stages of premature lung disease focus on minimizing alveolar damage. As infants grow and lung disease progresses, it becomes necessary to shift respiratory support to a strategy targeting the often severe pulmonary heterogeneity and obstructive respiratory physiology. With appropriate management, time, and growth, even those children with the most extreme prematurity and severe lung disease can be expected to wean from respiratory support. |
| first_indexed | 2024-04-10T06:15:08Z |
| format | Article |
| id | doaj.art-676ce74935c944dc9f588ef76656b49a |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-10T06:15:08Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-676ce74935c944dc9f588ef76656b49a2023-03-02T08:05:34ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-03-011110.3389/fped.2023.10878571087857Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasiaErik B. Hysinger0Shawn K. Ahlfeld1Division of Pulmonary Medicine, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United StatesDivision of Neonatology, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United StatesNeonates who are born preterm frequently have inadequate lung development to support independent breathing and will need respiratory support. The underdeveloped lung is also particularly susceptible to lung injury, especially during the first weeks of life. Consequently, respiratory support strategies in the early stages of premature lung disease focus on minimizing alveolar damage. As infants grow and lung disease progresses, it becomes necessary to shift respiratory support to a strategy targeting the often severe pulmonary heterogeneity and obstructive respiratory physiology. With appropriate management, time, and growth, even those children with the most extreme prematurity and severe lung disease can be expected to wean from respiratory support.https://www.frontiersin.org/articles/10.3389/fped.2023.1087857/fullprematuritybronchopulmonary dysplasiaCPAPmechanical ventilationtracheostomy |
| spellingShingle | Erik B. Hysinger Shawn K. Ahlfeld Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia Frontiers in Pediatrics prematurity bronchopulmonary dysplasia CPAP mechanical ventilation tracheostomy |
| title | Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| title_full | Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| title_fullStr | Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| title_full_unstemmed | Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| title_short | Respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| title_sort | respiratory support strategies in the prevention and treatment of bronchopulmonary dysplasia |
| topic | prematurity bronchopulmonary dysplasia CPAP mechanical ventilation tracheostomy |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1087857/full |
| work_keys_str_mv | AT erikbhysinger respiratorysupportstrategiesinthepreventionandtreatmentofbronchopulmonarydysplasia AT shawnkahlfeld respiratorysupportstrategiesinthepreventionandtreatmentofbronchopulmonarydysplasia |