Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding
Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori-negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2023-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2023/8244696 |
| _version_ | 1797855332633935872 |
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| author | Seo Hyun Kim Youssef Soliman Vikas N. Chitnavis Maithili V. Chitnavis |
| author_facet | Seo Hyun Kim Youssef Soliman Vikas N. Chitnavis Maithili V. Chitnavis |
| author_sort | Seo Hyun Kim |
| collection | DOAJ |
| description | Mucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori-negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with H. pylori-negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the t (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy. |
| first_indexed | 2024-04-09T20:22:04Z |
| format | Article |
| id | doaj.art-67715ba0e67d434fae9813cadd94a831 |
| institution | Directory Open Access Journal |
| issn | 2090-6536 |
| language | English |
| last_indexed | 2024-04-09T20:22:04Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj.art-67715ba0e67d434fae9813cadd94a8312023-03-31T00:00:01ZengHindawi LimitedCase Reports in Gastrointestinal Medicine2090-65362023-01-01202310.1155/2023/8244696Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal BleedingSeo Hyun Kim0Youssef Soliman1Vikas N. Chitnavis2Maithili V. Chitnavis3Virginia Tech Carilion School of MedicineGastroenterologyDepartment of Internal MedicineInflammatory Bowel Disease SectionMucosa-associated lymphoid tissue (MALT) lymphoma is a common cause of gastric lymphoma. Although most cases are associated with an H. pylori infection, approximately 10% are H. pylori-negative. Patients with gastric MALT lymphoma are usually asymptomatic or present with nonspecific symptoms such as abdominal pain, dyspepsia, weight loss, and occult gastrointestinal bleeding. In this report, we describe two patients with H. pylori-negative MALT lymphoma who both presented with acute upper gastrointestinal bleeding that led to hemodynamic instability. After resuscitation, emergent endoscopy was performed. Both patients had the t (11; 18) (q21; q21) translocation, which prompted direct treatment by radiotherapy.http://dx.doi.org/10.1155/2023/8244696 |
| spellingShingle | Seo Hyun Kim Youssef Soliman Vikas N. Chitnavis Maithili V. Chitnavis Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding Case Reports in Gastrointestinal Medicine |
| title | Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding |
| title_full | Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding |
| title_fullStr | Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding |
| title_full_unstemmed | Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding |
| title_short | Helicobacter Pylori-Negative MALT Lymphoma: A Series of Two Cases Presenting with Life-Threatening Upper Gastrointestinal Bleeding |
| title_sort | helicobacter pylori negative malt lymphoma a series of two cases presenting with life threatening upper gastrointestinal bleeding |
| url | http://dx.doi.org/10.1155/2023/8244696 |
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