Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior
Background: To “limit the risk of abuse and misuse” and “encourage correct usage”, the French drug regulatory authority stated that—from April 2017—zolpidem prescription must be performed on a secured prescription pad. This national study aims to evaluate the perception of general practitioners (GPs...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/8/2176 |
| _version_ | 1797445673950380032 |
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| author | Edouard-Jules Laforgue Marion Istvan Benoit Schreck Marie Mainguy Pascale Jolliet Marie Grall-Bronnec Caroline Victorri-Vigneau |
| author_facet | Edouard-Jules Laforgue Marion Istvan Benoit Schreck Marie Mainguy Pascale Jolliet Marie Grall-Bronnec Caroline Victorri-Vigneau |
| author_sort | Edouard-Jules Laforgue |
| collection | DOAJ |
| description | Background: To “limit the risk of abuse and misuse” and “encourage correct usage”, the French drug regulatory authority stated that—from April 2017—zolpidem prescription must be performed on a secured prescription pad. This national study aims to evaluate the perception of general practitioners (GPs) towards this new regulation and its link with prescription strategies. Methods: We conducted structured interviews of GPs. Data were collected about GPs’ perception of the measure and therapeutic strategies towards zolpidem. The primary outcome was the description of the GPs’ strategy of prescription, based on the perception towards the new regulation for zolpidem. Results: For 206 GPs, the new regulation was mainly perceived as helpful (61%) and as a difficulty (55%). Other perceptions were the awareness of the risks of zolpidem (18%), awareness of the risks of hypnotics (13%), and nothing changed (5%). Four clusters of GPs were identified. In the clusters with the perception as a difficulty (only or associated with helpful), the GPs who applied the strategy “no modification” for >50% of their patients were more frequently compared to awareness and helpful only clusters (60.8%; 42.9%; 20.4%; 26.7%) (<i>p</i> < 0.001). Conclusions: We highlighted an association between the perception of the new regulation of zolpidem prescription by GPs and a strategy of prescription. |
| first_indexed | 2024-03-09T13:30:10Z |
| format | Article |
| id | doaj.art-6771663d14514cd181f74caf51fab722 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T13:30:10Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-6771663d14514cd181f74caf51fab7222023-11-30T21:19:28ZengMDPI AGJournal of Clinical Medicine2077-03832022-04-01118217610.3390/jcm11082176Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription BehaviorEdouard-Jules Laforgue0Marion Istvan1Benoit Schreck2Marie Mainguy3Pascale Jolliet4Marie Grall-Bronnec5Caroline Victorri-Vigneau6Nantes Université, CHU Nantes, Service de Pharmacologie Clinique—Centre d’Évaluation et d’Information sur la Pharmacovigilance-Addictovigilance, F-44000 Nantes, FranceNantes Université, CHU Nantes, Service de Pharmacologie Clinique—Centre d’Évaluation et d’Information sur la Pharmacovigilance-Addictovigilance, F-44000 Nantes, FranceNantes Université, Univ Tours, CHU Nantes, CHU Tours, INSERM, MethodS in Patients-Centered Outcomes and HEalth Research, SPHERE, F-44000 Nantes, FranceNantes Université, CHU Nantes, Service de Pharmacologie Clinique—Centre d’Évaluation et d’Information sur la Pharmacovigilance-Addictovigilance, F-44000 Nantes, FranceNantes Université, CHU Nantes, Service de Pharmacologie Clinique—Centre d’Évaluation et d’Information sur la Pharmacovigilance-Addictovigilance, F-44000 Nantes, FranceNantes Université, Univ Tours, CHU Nantes, CHU Tours, INSERM, MethodS in Patients-Centered Outcomes and HEalth Research, SPHERE, F-44000 Nantes, FranceNantes Université, CHU Nantes, Service de Pharmacologie Clinique—Centre d’Évaluation et d’Information sur la Pharmacovigilance-Addictovigilance, F-44000 Nantes, FranceBackground: To “limit the risk of abuse and misuse” and “encourage correct usage”, the French drug regulatory authority stated that—from April 2017—zolpidem prescription must be performed on a secured prescription pad. This national study aims to evaluate the perception of general practitioners (GPs) towards this new regulation and its link with prescription strategies. Methods: We conducted structured interviews of GPs. Data were collected about GPs’ perception of the measure and therapeutic strategies towards zolpidem. The primary outcome was the description of the GPs’ strategy of prescription, based on the perception towards the new regulation for zolpidem. Results: For 206 GPs, the new regulation was mainly perceived as helpful (61%) and as a difficulty (55%). Other perceptions were the awareness of the risks of zolpidem (18%), awareness of the risks of hypnotics (13%), and nothing changed (5%). Four clusters of GPs were identified. In the clusters with the perception as a difficulty (only or associated with helpful), the GPs who applied the strategy “no modification” for >50% of their patients were more frequently compared to awareness and helpful only clusters (60.8%; 42.9%; 20.4%; 26.7%) (<i>p</i> < 0.001). Conclusions: We highlighted an association between the perception of the new regulation of zolpidem prescription by GPs and a strategy of prescription.https://www.mdpi.com/2077-0383/11/8/2176zolpidemdrug regulationperceptiongeneral practitionerprescription behavior |
| spellingShingle | Edouard-Jules Laforgue Marion Istvan Benoit Schreck Marie Mainguy Pascale Jolliet Marie Grall-Bronnec Caroline Victorri-Vigneau Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior Journal of Clinical Medicine zolpidem drug regulation perception general practitioner prescription behavior |
| title | Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior |
| title_full | Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior |
| title_fullStr | Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior |
| title_full_unstemmed | Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior |
| title_short | Perception of the Regulatory Change for Zolpidem Prescription by French General Practitioners and Its Relation to Prescription Behavior |
| title_sort | perception of the regulatory change for zolpidem prescription by french general practitioners and its relation to prescription behavior |
| topic | zolpidem drug regulation perception general practitioner prescription behavior |
| url | https://www.mdpi.com/2077-0383/11/8/2176 |
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