Induction of Angiogenesis in Zebrafish Embryos and Proliferation of Endothelial Cells by an Active Fraction Isolated from the Root of Astragalus membranaceus using Bioassay-guided Fractionation

Induction of Angiogenesis in Zebrafish Embryos and Proliferation of Endothelial Cells by an Active Fraction Isolated from the Root of Astragalus membranaceus using Bioassay-guided Fractionation

The objective of the study was to identify the active fraction(s) from AR aqueous extract responsible for promoting angiogenesis using bioassay-guided fractionation. The angiogenic activity was screened by monitoring the increase of sprout number in sub-intestinal vessel (SIV) of the transgenic zebr...

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Bibliographic Details
Main Authors: Patrick Kwok-Kin Lai, Judy Yuet-Wa Chan, Hin-Fai Kwok, Ling Cheng, Hua Yu, Ching-Po Lau, Ping-Chung Leung, Kwok-Pui Fung, Clara Bik-San Lau
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Journal of Traditional and Complementary Medicine
Subjects:
Astragali Radix
Glycoproteins
Traditional Chinese Medicine
Wound healing
Online Access:http://www.sciencedirect.com/science/article/pii/S2225411016302383

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