Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease
Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/13/10/1506 |
| _version_ | 1827721515244716032 |
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| author | Jaehyun Bae Byung-Wan Lee |
| author_facet | Jaehyun Bae Byung-Wan Lee |
| author_sort | Jaehyun Bae |
| collection | DOAJ |
| description | Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association. |
| first_indexed | 2024-03-10T21:24:30Z |
| format | Article |
| id | doaj.art-6777abd65d3c4ff9ac28e0e6911722d8 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T21:24:30Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-6777abd65d3c4ff9ac28e0e6911722d82023-11-19T15:50:13ZengMDPI AGBiomolecules2218-273X2023-10-011310150610.3390/biom13101506Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver DiseaseJaehyun Bae0Byung-Wan Lee1Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic Kwandong University College of Medicine, International St. Mary’s Hospital, Incheon 22711, Republic of KoreaDivision of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of KoreaMetabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.https://www.mdpi.com/2218-273X/13/10/1506ketoneketogenesismetabolic-associated fatty liver disease |
| spellingShingle | Jaehyun Bae Byung-Wan Lee Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease Biomolecules ketone ketogenesis metabolic-associated fatty liver disease |
| title | Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease |
| title_full | Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease |
| title_fullStr | Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease |
| title_full_unstemmed | Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease |
| title_short | Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease |
| title_sort | association between impaired ketogenesis and metabolic associated fatty liver disease |
| topic | ketone ketogenesis metabolic-associated fatty liver disease |
| url | https://www.mdpi.com/2218-273X/13/10/1506 |
| work_keys_str_mv | AT jaehyunbae associationbetweenimpairedketogenesisandmetabolicassociatedfattyliverdisease AT byungwanlee associationbetweenimpairedketogenesisandmetabolicassociatedfattyliverdisease |