Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing
Abstract This study proposes a highly sensitive portable device that utilizes electromagnetic waves and data analytics for instantaneous Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS‐CoV‐2) detection. The device consists of a Radio Frequency (RF) circuit that interprets reflected and transmi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley-VCH
2024-04-01
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| Series: | Advanced Sensor Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/adsr.202300135 |
| _version_ | 1797214287969648640 |
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| author | Rayan Al Sayed Ali Nader Shafi Fatima Asadallah Rachel Njeim Habib Al Kalamouni Hassan Zaraket Rouwaida Kanj Assaad Eid Joseph Costantine Youssef Tawk |
| author_facet | Rayan Al Sayed Ali Nader Shafi Fatima Asadallah Rachel Njeim Habib Al Kalamouni Hassan Zaraket Rouwaida Kanj Assaad Eid Joseph Costantine Youssef Tawk |
| author_sort | Rayan Al Sayed Ali |
| collection | DOAJ |
| description | Abstract This study proposes a highly sensitive portable device that utilizes electromagnetic waves and data analytics for instantaneous Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS‐CoV‐2) detection. The device consists of a Radio Frequency (RF) circuit that interprets reflected and transmitted electromagnetic waves to identify virus signatures in physiologically significant matrices, including human saliva and diluted nasopharyngeal swabs. The sensor's accuracy is validated in both pre‐clinical and clinical settings, where clinical measurements demonstrate an instantaneous detection accuracy of 94%, sensitivity of 95%, and specificity of 97.5% between the sensor's physical parameters and SARS‐CoV‐2 detection. The sensor's accurate real‐time response is due to its unique design and precise modeling techniques. In addition, the same sensing system is tested across different viruses and its ability to differentiate between influenza A, respiratory syncytial, and SARS‐CoV‐2 viruses is proven. Hence this work presents a holistic system that can predict the viral concentration of SARS‐CoV‐2, as well as differentiate between different viruses instantaneously and without adding any amplifying agent. |
| first_indexed | 2024-04-24T11:11:47Z |
| format | Article |
| id | doaj.art-67792cdbd7f84ce8a1cb6d3d13b518e4 |
| institution | Directory Open Access Journal |
| issn | 2751-1219 |
| language | English |
| last_indexed | 2024-04-24T11:11:47Z |
| publishDate | 2024-04-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Advanced Sensor Research |
| spelling | doaj.art-67792cdbd7f84ce8a1cb6d3d13b518e42024-04-11T13:29:08ZengWiley-VCHAdvanced Sensor Research2751-12192024-04-0134n/an/a10.1002/adsr.202300135Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic SensingRayan Al Sayed Ali0Nader Shafi1Fatima Asadallah2Rachel Njeim3Habib Al Kalamouni4Hassan Zaraket5Rouwaida Kanj6Assaad Eid7Joseph Costantine8Youssef Tawk9Department of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonDepartment of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonDepartment of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonDepartment of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine American University of Beirut Beirut 1107‐2020 LebanonDepartment of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine American University of Beirut Beirut 1107‐2020 LebanonDepartment of Experimental Pathology, Immunology, and Microbiology, Faculty of Medicine American University of Beirut Beirut 1107‐2020 LebanonDepartment of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonDepartment of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine American University of Beirut Beirut 1107‐2020 LebanonDepartment of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonDepartment of Electrical and Computer Engineering, Maroun Semaan Faculty of Engineering and Architecture American University of Beirut Beirut 1107‐2020 LebanonAbstract This study proposes a highly sensitive portable device that utilizes electromagnetic waves and data analytics for instantaneous Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS‐CoV‐2) detection. The device consists of a Radio Frequency (RF) circuit that interprets reflected and transmitted electromagnetic waves to identify virus signatures in physiologically significant matrices, including human saliva and diluted nasopharyngeal swabs. The sensor's accuracy is validated in both pre‐clinical and clinical settings, where clinical measurements demonstrate an instantaneous detection accuracy of 94%, sensitivity of 95%, and specificity of 97.5% between the sensor's physical parameters and SARS‐CoV‐2 detection. The sensor's accurate real‐time response is due to its unique design and precise modeling techniques. In addition, the same sensing system is tested across different viruses and its ability to differentiate between influenza A, respiratory syncytial, and SARS‐CoV‐2 viruses is proven. Hence this work presents a holistic system that can predict the viral concentration of SARS‐CoV‐2, as well as differentiate between different viruses instantaneously and without adding any amplifying agent.https://doi.org/10.1002/adsr.202300135instantaneous viral detectionmicrowave resonatorsmicrowave sensornon‐chemicalSARS‐CoV‐2 |
| spellingShingle | Rayan Al Sayed Ali Nader Shafi Fatima Asadallah Rachel Njeim Habib Al Kalamouni Hassan Zaraket Rouwaida Kanj Assaad Eid Joseph Costantine Youssef Tawk Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing Advanced Sensor Research instantaneous viral detection microwave resonators microwave sensor non‐chemical SARS‐CoV‐2 |
| title | Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing |
| title_full | Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing |
| title_fullStr | Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing |
| title_full_unstemmed | Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing |
| title_short | Instantaneous Viral Detection of SARS‐CoV‐2 and Beyond using Electromagnetic Sensing |
| title_sort | instantaneous viral detection of sars cov 2 and beyond using electromagnetic sensing |
| topic | instantaneous viral detection microwave resonators microwave sensor non‐chemical SARS‐CoV‐2 |
| url | https://doi.org/10.1002/adsr.202300135 |
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