Epigenetic control of the foxp3 locus in regulatory T cells.

Epigenetic control of the foxp3 locus in regulatory T cells.

Compelling evidence suggests that the transcription factor Foxp3 acts as a master switch governing the development and function of CD4(+) regulatory T cells (Tregs). However, whether transcriptional control of Foxp3 expression itself contributes to the development of a stable Treg lineage has thus f...

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Main Authors: Stefan Floess, Jennifer Freyer, Christiane Siewert, Udo Baron, Sven Olek, Julia Polansky, Kerstin Schlawe, Hyun-Dong Chang, Tobias Bopp, Edgar Schmitt, Stefan Klein-Hessling, Edgar Serfling, Alf Hamann, Jochen Huehn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1783672?pdf=render

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