Kinase and Phosphatase Cross-Talk at the Kinetochore

Kinase and Phosphatase Cross-Talk at the Kinetochore

Multiple kinases and phosphatases act on the kinetochore to control chromosome segregation: Aurora B, Mps1, Bub1, Plk1, Cdk1, PP1, and PP2A-B56, have all been shown to regulate both kinetochore-microtubule attachments and the spindle assembly checkpoint. Given that so many kinases and phosphatases c...

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Bibliographic Details
Main Author:	Adrian T. Saurin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-06-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	kinase phosphatase spindle assembly checkpoint kinetochore Cdk1 PP2A
Online Access:	https://www.frontiersin.org/article/10.3389/fcell.2018.00062/full

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