Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population
BackgroundTwo indices: visceral adiposity index (VAI) and atherogenic index of plasma (AIP) during several recent years were implemented into epidemiological studies for predicting of cardiovascular diseases (CVD) and mortality risk. Our study aimed to evaluate the association of VAI and AIP with th...
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1150563/full |
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| author | Abdonas Tamosiunas Dalia Luksiene Dalia Luksiene Daina Kranciukaite-Butylkiniene Daina Kranciukaite-Butylkiniene Ricardas Radisauskas Ricardas Radisauskas Diana Sopagiene Martin Bobak |
| author_facet | Abdonas Tamosiunas Dalia Luksiene Dalia Luksiene Daina Kranciukaite-Butylkiniene Daina Kranciukaite-Butylkiniene Ricardas Radisauskas Ricardas Radisauskas Diana Sopagiene Martin Bobak |
| author_sort | Abdonas Tamosiunas |
| collection | DOAJ |
| description | BackgroundTwo indices: visceral adiposity index (VAI) and atherogenic index of plasma (AIP) during several recent years were implemented into epidemiological studies for predicting of cardiovascular diseases (CVD) and mortality risk. Our study aimed to evaluate the association of VAI and AIP with the risk of all-cause and CVD mortality among the Lithuanian urban population aged 45–72 years.MethodsIn the baseline survey (2006–2008), 7,115 men and women 45–72 years of age were examined within the framework of the international study Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE). Six thousand six hundred and seventy-one participants (3,663 women and 3,008 men) were available for statistical analysis (after excluding 429 respondents with the missed information on study variables) and for them, VAI and AIP were calculated. The questionnaire evaluated lifestyle behaviors, including smoking and physical activity. All participants in the baseline survey were followed up for all-cause and CVD mortality events until December 31st, 2020. Multivariable Cox regression models were applied for statistical data analysis.ResultsAfter accounting for several potential confounders, higher levels of VAI (compared 5th quintile to 1st quintile) were associated with significantly higher CVD mortality in men [Hazards ratio (HR) = 1.38] and all-cause mortality in women (HR = 1.54) after 10-year follow-up. CVD mortality significantly increased in men with 0 the highest AIP quintile compared with that for the lowest quintile (HR = 1.40). In women, all-cause mortality was significantly higher for the 4th quintile of AIP as compared with the 1st quintile (HR = 1.36).ConclusionsHigh-risk VAI levels were statistically significantly associated with all-cause mortality risk in men and women groups. The higher AIP level (5th quintile vs. 1st quintile—in men and 4th quintile vs. 1st quintile—in women) was significantly associated with increased mortality from CVD in the men group and increased all-cause mortality in the women group. |
| first_indexed | 2024-04-10T04:07:11Z |
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| id | doaj.art-67825c6f634a40e0a499085bc8b78e2e |
| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-04-10T04:07:11Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-67825c6f634a40e0a499085bc8b78e2e2023-03-13T05:06:34ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-03-011110.3389/fpubh.2023.11505631150563Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian populationAbdonas Tamosiunas0Dalia Luksiene1Dalia Luksiene2Daina Kranciukaite-Butylkiniene3Daina Kranciukaite-Butylkiniene4Ricardas Radisauskas5Ricardas Radisauskas6Diana Sopagiene7Martin Bobak8Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaInstitute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaDepartment of Environmental and Occupational Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaInstitute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaDepartment of Family Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaInstitute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaDepartment of Environmental and Occupational Medicine, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaDepartment of Radiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LithuaniaInstitute of Epidemiology and Health Care, University College London, London, United KingdomBackgroundTwo indices: visceral adiposity index (VAI) and atherogenic index of plasma (AIP) during several recent years were implemented into epidemiological studies for predicting of cardiovascular diseases (CVD) and mortality risk. Our study aimed to evaluate the association of VAI and AIP with the risk of all-cause and CVD mortality among the Lithuanian urban population aged 45–72 years.MethodsIn the baseline survey (2006–2008), 7,115 men and women 45–72 years of age were examined within the framework of the international study Health, Alcohol and Psychosocial Factors in Eastern Europe (HAPIEE). Six thousand six hundred and seventy-one participants (3,663 women and 3,008 men) were available for statistical analysis (after excluding 429 respondents with the missed information on study variables) and for them, VAI and AIP were calculated. The questionnaire evaluated lifestyle behaviors, including smoking and physical activity. All participants in the baseline survey were followed up for all-cause and CVD mortality events until December 31st, 2020. Multivariable Cox regression models were applied for statistical data analysis.ResultsAfter accounting for several potential confounders, higher levels of VAI (compared 5th quintile to 1st quintile) were associated with significantly higher CVD mortality in men [Hazards ratio (HR) = 1.38] and all-cause mortality in women (HR = 1.54) after 10-year follow-up. CVD mortality significantly increased in men with 0 the highest AIP quintile compared with that for the lowest quintile (HR = 1.40). In women, all-cause mortality was significantly higher for the 4th quintile of AIP as compared with the 1st quintile (HR = 1.36).ConclusionsHigh-risk VAI levels were statistically significantly associated with all-cause mortality risk in men and women groups. The higher AIP level (5th quintile vs. 1st quintile—in men and 4th quintile vs. 1st quintile—in women) was significantly associated with increased mortality from CVD in the men group and increased all-cause mortality in the women group.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1150563/fullvisceral adiposity indexatherogenic index of plasmacardiovascular diseasesmortalitygender |
| spellingShingle | Abdonas Tamosiunas Dalia Luksiene Dalia Luksiene Daina Kranciukaite-Butylkiniene Daina Kranciukaite-Butylkiniene Ricardas Radisauskas Ricardas Radisauskas Diana Sopagiene Martin Bobak Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population Frontiers in Public Health visceral adiposity index atherogenic index of plasma cardiovascular diseases mortality gender |
| title | Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population |
| title_full | Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population |
| title_fullStr | Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population |
| title_full_unstemmed | Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population |
| title_short | Predictive importance of the visceral adiposity index and atherogenic index of plasma of all-cause and cardiovascular disease mortality in middle-aged and elderly Lithuanian population |
| title_sort | predictive importance of the visceral adiposity index and atherogenic index of plasma of all cause and cardiovascular disease mortality in middle aged and elderly lithuanian population |
| topic | visceral adiposity index atherogenic index of plasma cardiovascular diseases mortality gender |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1150563/full |
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