Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities

In 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the manag...

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Main Authors: Renren Yang, Jia Tang, Yunping Zhuo, Ming Kuang, Hongying Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-04-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2021.2022688
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author Renren Yang
Jia Tang
Yunping Zhuo
Ming Kuang
Hongying Liu
author_facet Renren Yang
Jia Tang
Yunping Zhuo
Ming Kuang
Hongying Liu
author_sort Renren Yang
collection DOAJ
description In 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the management of hypertension. To evaluate adherence to the guidelines, this retrospective study assessed the real-world status of antihypertensive drug prescribing for Chinese patients with hypertension, classified by comorbidity: coronary heart disease, diabetes mellitus, heart failure, stroke, and renal disease. About 1088212 hypertensive patients who received their first prescription for antihypertensive therapy between January 2021 to June 2021, were obtained from a database of Hangzhou Kang Sheng Health Consulting CO., Ltd. Calcium channel blockers (CCBs) and angiotensin II receptor blockers (ARBs) were the most common drugs prescribed for each comorbidity subgroup. Whereas diabetes mellitus or renal disease is a compelling indication for use of renin–angiotensin system inhibitors, CCBs were often administered in these subgroups. The treatment pattern for patients with coronary heart disease was closely similar to that for the overall patient population. Beta-blockers (BBs) were prescribed more frequently for patients with heart failure than for those with other comorbidities. Although antihypertensive drug prescription varied by comorbidity, pharmacological decisions were largely made under Chinese recommendations while physicians could select antihypertensive drugs based on the patients’ comorbidities. However, educational initiatives are still necessary to inspire clinicians to better familiarize themselves with the guidelines and manage hypertension comorbid diseases.
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spelling doaj.art-67870dadef264576aa32416996aa0b7b2023-09-19T16:04:07ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062022-04-0144324024810.1080/10641963.2021.20226882022688Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbiditiesRenren Yang0Jia Tang1Yunping Zhuo2Ming Kuang3Hongying Liu4Hangzhou Kang Sheng Health Consulting CO., LtdHangzhou Kang Sheng Health Consulting CO., LtdHangzhou Kang Sheng Health Consulting CO., LtdHangzhou Kang Sheng Health Consulting CO., LtdHangzhou Kang Sheng Health Consulting CO., LtdIn 2020, the National Center for Cardiovascular Diseases with National Committee on Hypertension Management in Primary Health Care in China issued revised national clinical practice guidelines on the management of hypertension in primary health care based on the 2018 Chinese guidelines for the management of hypertension. To evaluate adherence to the guidelines, this retrospective study assessed the real-world status of antihypertensive drug prescribing for Chinese patients with hypertension, classified by comorbidity: coronary heart disease, diabetes mellitus, heart failure, stroke, and renal disease. About 1088212 hypertensive patients who received their first prescription for antihypertensive therapy between January 2021 to June 2021, were obtained from a database of Hangzhou Kang Sheng Health Consulting CO., Ltd. Calcium channel blockers (CCBs) and angiotensin II receptor blockers (ARBs) were the most common drugs prescribed for each comorbidity subgroup. Whereas diabetes mellitus or renal disease is a compelling indication for use of renin–angiotensin system inhibitors, CCBs were often administered in these subgroups. The treatment pattern for patients with coronary heart disease was closely similar to that for the overall patient population. Beta-blockers (BBs) were prescribed more frequently for patients with heart failure than for those with other comorbidities. Although antihypertensive drug prescription varied by comorbidity, pharmacological decisions were largely made under Chinese recommendations while physicians could select antihypertensive drugs based on the patients’ comorbidities. However, educational initiatives are still necessary to inspire clinicians to better familiarize themselves with the guidelines and manage hypertension comorbid diseases.http://dx.doi.org/10.1080/10641963.2021.2022688antihypertensive drugshypertensioncomorbiditytreatment patternreal-world data
spellingShingle Renren Yang
Jia Tang
Yunping Zhuo
Ming Kuang
Hongying Liu
Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
Clinical and Experimental Hypertension
antihypertensive drugs
hypertension
comorbidity
treatment pattern
real-world data
title Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
title_full Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
title_fullStr Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
title_full_unstemmed Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
title_short Current prescription status of antihypertensive drugs in Chinese patients with hypertension: analysis by type of comorbidities
title_sort current prescription status of antihypertensive drugs in chinese patients with hypertension analysis by type of comorbidities
topic antihypertensive drugs
hypertension
comorbidity
treatment pattern
real-world data
url http://dx.doi.org/10.1080/10641963.2021.2022688
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