The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

The Potential of Telomeric G-Quadruplexes Containing Modified Oligoguanosine Overhangs in Activation of Bacterial Phagocytosis and Leukotriene Synthesis in Human Neutrophils

Human neutrophils are the first line of defense against bacterial and viral infections. They eliminate pathogens through phagocytosis, which activate the 5-lipoxygenase (5-LOX) pathway resulting in synthesis of leukotrienes. Using HPLC analysis, flow cytometry, and other biochemical methods, we stud...

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Bibliographic Details
Main Authors: Ekaterina A. Golenkina, Galina M. Viryasova, Nina G. Dolinnaya, Valeria A. Bannikova, Tatjana V. Gaponova, Yulia M. Romanova, Galina F. Sud’ina
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
neutrophils
phagocytosis
leukotrienes
oligodeoxyribonucleotides
g-quadruplexes
salmonella
Online Access:https://www.mdpi.com/2218-273X/10/2/249

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