Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain
Fatty acid composition across functional brain regions was determined in bovine brains collected from cattle that were provided supplements of calcium salts containing either palm or fish oil. The Angus cattle were divided into two groups, with one group offered the supplement of calcium salts of pa...
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| Format: | Article |
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MDPI AG
2022-10-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/19/2696 |
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| author | Daniel C. Rule Emily A. Melson Brenda M. Alexander Travis E. Brown |
| author_facet | Daniel C. Rule Emily A. Melson Brenda M. Alexander Travis E. Brown |
| author_sort | Daniel C. Rule |
| collection | DOAJ |
| description | Fatty acid composition across functional brain regions was determined in bovine brains collected from cattle that were provided supplements of calcium salts containing either palm or fish oil. The Angus cattle were divided into two groups, with one group offered the supplement of calcium salts of palm oil and the other offered the calcium salts of fish oil (n = 5 females and n = 5 males/supplement) for 220 days. These supplements to the basal forage diet were provided ad libitum as a suspension in dried molasses. The fish oil exclusively provided eicosapentaenoic acid (EPA, C20:5 n-3) and docosahexaenoic acid (DHA, C22:6 n-3). The functional regions were dissected from the entire brains following commercial harvest. While the cattle provided diets supplemented with the calcium salts of palm oil had increased (<i>p</i> < 0.01) liver concentrations of C18:1 n-9, C18:2 n-6, and arachidonic acid, the fish-oil-supplemented cattle had greater (<i>p</i> < 0.01) concentrations of liver EPA, DHA, and C18:3 n-3. In the brain, DHA was the most abundant polyunsaturated fatty acid. In the amygdala, pons, frontal lobe, internal capsule, and sensory cortex, DHA concentrations were greater (<i>p</i> < 0.05) in the brains of the cattle fed fish oil. Differences among the supplements were small, indicating that brain DHA content is resistant to dietary change. Arachidonic acid and C22:4 n-6 concentrations were greater across the regions for the palm-oil-supplemented cattle. EPA and C22:5 n-3 concentrations were low, but they were greater across the regions for the cattle fed fish oil. The effects of sex were inconsistent. The fatty acid profiles of the brain regions differed by diet, but they were similar to the contents reported for other species. |
| first_indexed | 2024-03-09T22:07:26Z |
| format | Article |
| id | doaj.art-678b59ab482f4e7c8272ac4e671329e1 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T22:07:26Z |
| publishDate | 2022-10-01 |
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| record_format | Article |
| series | Animals |
| spelling | doaj.art-678b59ab482f4e7c8272ac4e671329e12023-11-23T19:38:14ZengMDPI AGAnimals2076-26152022-10-011219269610.3390/ani12192696Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine BrainDaniel C. Rule0Emily A. Melson1Brenda M. Alexander2Travis E. Brown3Department of Animal Science, University of Wyoming, Laramie, WY 82071, USADepartment of Animal Science, University of Wyoming, Laramie, WY 82071, USADepartment of Animal Science, University of Wyoming, Laramie, WY 82071, USADepartment of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA 99164, USAFatty acid composition across functional brain regions was determined in bovine brains collected from cattle that were provided supplements of calcium salts containing either palm or fish oil. The Angus cattle were divided into two groups, with one group offered the supplement of calcium salts of palm oil and the other offered the calcium salts of fish oil (n = 5 females and n = 5 males/supplement) for 220 days. These supplements to the basal forage diet were provided ad libitum as a suspension in dried molasses. The fish oil exclusively provided eicosapentaenoic acid (EPA, C20:5 n-3) and docosahexaenoic acid (DHA, C22:6 n-3). The functional regions were dissected from the entire brains following commercial harvest. While the cattle provided diets supplemented with the calcium salts of palm oil had increased (<i>p</i> < 0.01) liver concentrations of C18:1 n-9, C18:2 n-6, and arachidonic acid, the fish-oil-supplemented cattle had greater (<i>p</i> < 0.01) concentrations of liver EPA, DHA, and C18:3 n-3. In the brain, DHA was the most abundant polyunsaturated fatty acid. In the amygdala, pons, frontal lobe, internal capsule, and sensory cortex, DHA concentrations were greater (<i>p</i> < 0.05) in the brains of the cattle fed fish oil. Differences among the supplements were small, indicating that brain DHA content is resistant to dietary change. Arachidonic acid and C22:4 n-6 concentrations were greater across the regions for the palm-oil-supplemented cattle. EPA and C22:5 n-3 concentrations were low, but they were greater across the regions for the cattle fed fish oil. The effects of sex were inconsistent. The fatty acid profiles of the brain regions differed by diet, but they were similar to the contents reported for other species.https://www.mdpi.com/2076-2615/12/19/2696bovineDHAEPAarachidonic acidfish oilpalm oil |
| spellingShingle | Daniel C. Rule Emily A. Melson Brenda M. Alexander Travis E. Brown Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain Animals bovine DHA EPA arachidonic acid fish oil palm oil |
| title | Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain |
| title_full | Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain |
| title_fullStr | Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain |
| title_full_unstemmed | Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain |
| title_short | Dietary Fatty Acid Composition Impacts the Fatty Acid Profiles of Different Regions of the Bovine Brain |
| title_sort | dietary fatty acid composition impacts the fatty acid profiles of different regions of the bovine brain |
| topic | bovine DHA EPA arachidonic acid fish oil palm oil |
| url | https://www.mdpi.com/2076-2615/12/19/2696 |
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