The role of opioid peptides in the regulation of secretin-stimulated bile secretion

Influence of intraperitoneal dalargin (dand m-opioid agonist), DADLE (d-opioid agonist), DAGO (m-opioid agonist) and U50488 (k-opioid agonist) on bile secretion which is stimulated by secretin was studied in sharp experiments on white rats. All opioids studied is demonstrated to suppress secretory r...

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Main Authors: M. A. Medvedev, I. V. Roudin
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2006-09-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3087
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author M. A. Medvedev
I. V. Roudin
author_facet M. A. Medvedev
I. V. Roudin
author_sort M. A. Medvedev
collection DOAJ
description Influence of intraperitoneal dalargin (dand m-opioid agonist), DADLE (d-opioid agonist), DAGO (m-opioid agonist) and U50488 (k-opioid agonist) on bile secretion which is stimulated by secretin was studied in sharp experiments on white rats. All opioids studied is demonstrated to suppress secretory response of liver upon secretin in different extent. We suppose that opioidergic regulation system has different effect on bile secretion in dependence of baseline level of physiologic secretion.
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spelling doaj.art-678b6697d4b64172b401035167b873712023-03-13T09:58:05ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842006-09-0153374110.20538/1682-0363-2006-3-37-411745The role of opioid peptides in the regulation of secretin-stimulated bile secretionM. A. Medvedev0I. V. Roudin1Сибирский государственный медицинский университетСибирский государственный медицинский университетInfluence of intraperitoneal dalargin (dand m-opioid agonist), DADLE (d-opioid agonist), DAGO (m-opioid agonist) and U50488 (k-opioid agonist) on bile secretion which is stimulated by secretin was studied in sharp experiments on white rats. All opioids studied is demonstrated to suppress secretory response of liver upon secretin in different extent. We suppose that opioidergic regulation system has different effect on bile secretion in dependence of baseline level of physiologic secretion.https://bulletin.ssmu.ru/jour/article/view/3087секретинопиоидные пептидысекреция желчиsecretinopioid peptidesbile secretion
spellingShingle M. A. Medvedev
I. V. Roudin
The role of opioid peptides in the regulation of secretin-stimulated bile secretion
Бюллетень сибирской медицины
секретин
опиоидные пептиды
секреция желчи
secretin
opioid peptides
bile secretion
title The role of opioid peptides in the regulation of secretin-stimulated bile secretion
title_full The role of opioid peptides in the regulation of secretin-stimulated bile secretion
title_fullStr The role of opioid peptides in the regulation of secretin-stimulated bile secretion
title_full_unstemmed The role of opioid peptides in the regulation of secretin-stimulated bile secretion
title_short The role of opioid peptides in the regulation of secretin-stimulated bile secretion
title_sort role of opioid peptides in the regulation of secretin stimulated bile secretion
topic секретин
опиоидные пептиды
секреция желчи
secretin
opioid peptides
bile secretion
url https://bulletin.ssmu.ru/jour/article/view/3087
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AT mamedvedev roleofopioidpeptidesintheregulationofsecretinstimulatedbilesecretion
AT ivroudin roleofopioidpeptidesintheregulationofsecretinstimulatedbilesecretion