HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways

HERPUD1 promotes ovarian cancer cell survival by sustaining autophagy and inhibit apoptosis via PI3K/AKT/mTOR and p38 MAPK signaling pathways

Abstract HERPUD1 is an important early marker of endoplasmic reticulum stress (ERS) and is involved in the ubiquitination and degradation of several unfolded proteins. However, its role in tumorigenesis is seldom studied, and its role in ovarian cancer is unclear. Lewis y antigen is a tumor-associat...

Full description

Bibliographic Details
Main Authors: Xin Nie, Dawo Liu, Mingjun Zheng, Xiao Li, Ouxuan Liu, Qian Guo, Liancheng Zhu, Bei Lin
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Cancer
Subjects:
HERPUD1
Ovarian cancer
PI3K
MAPK
Endoplasmic reticulum stress
Online Access:https://doi.org/10.1186/s12885-022-10248-5

Similar Items

Similar Items