The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings
Abstract Bacground/Aims: The aim of study to evaluate the effects of synthetic collagen membrane placed on dura mater on the prevention of arachnoiditis and fibrosis development by magnetic resonance imaging (MRI) findings in patients undergoing lumbar discectomy. Methods: A total of 40 patients who...
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| Format: | Article |
| Language: | English |
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Selçuk University
2023-06-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2942607 |
| _version_ | 1797688301353697280 |
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| author | Mehmet Kaya |
| author_facet | Mehmet Kaya |
| author_sort | Mehmet Kaya |
| collection | DOAJ |
| description | Abstract
Bacground/Aims: The aim of study to evaluate the effects of synthetic collagen membrane placed on dura mater on the prevention of arachnoiditis and fibrosis development by magnetic resonance imaging (MRI) findings in patients undergoing lumbar discectomy.
Methods: A total of 40 patients who underwent single level unilateral discectomy for lumbar disc hernia were retrospectively evaluated. Sixteen patients with collagen membranes placed on the dura and 24 patients without any material on the dura were included in the study. Postoperative MRI images of the patients with and without collagen membranes were examined and evaluated whether the material used was effective in preventing arachnoiditis and / or epidural fibrosis and granulation tissue formation.
Results: Nine female patients (37.5%) and 15 male patients (62.5%) of 24 patients were in the collagen membrane-free group. Four of the patients in the collagen membrane group were female (25%) and 12 were male (75%). The mean age of the non-membrane group was 35.47 ± 9.06, and the mean age of the membrane group was 37.40 ± 8.92 years. According to MRI findings, granulation tissue and epidural fibrosis were not observed in 8 (50%) of 16 patients with collagen membranes, whereas granulation tissue was observed in 8 (50%) patients. Granulation tissue was not observed in 10 (41.7%) of 24 patients without collagen membrane, whereas epidural fibrosis and granulation tissue formation was observed in 14 (58.3%). Based on these results, there was no statistically significant relationship between type-I collagen membrane use and granulation tissue formation. (P = 0.604 <0.05). There was no difference between the rate of granulation tissue (50%) and absence (50%) in patients with type-I collagen membranes.
Conclusion: According to these results and MRI findings, it was found that peroperative type-I collagen membrane use in lumbar discectomy did not have a statistically significant effect on granulation tissue or epidural fibrosis formation. |
| first_indexed | 2024-03-12T01:30:15Z |
| format | Article |
| id | doaj.art-678d9b509aef4574b6ee8fb8d63fa54c |
| institution | Directory Open Access Journal |
| issn | 2602-3741 |
| language | English |
| last_indexed | 2024-03-12T01:30:15Z |
| publishDate | 2023-06-01 |
| publisher | Selçuk University |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj.art-678d9b509aef4574b6ee8fb8d63fa54c2023-09-12T06:30:13ZengSelçuk UniversityGenel Tıp Dergisi2602-37412023-06-0133329930410.54005/geneltip.1248667154The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging FindingsMehmet Kaya0SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL TAKSİM SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜAbstract Bacground/Aims: The aim of study to evaluate the effects of synthetic collagen membrane placed on dura mater on the prevention of arachnoiditis and fibrosis development by magnetic resonance imaging (MRI) findings in patients undergoing lumbar discectomy. Methods: A total of 40 patients who underwent single level unilateral discectomy for lumbar disc hernia were retrospectively evaluated. Sixteen patients with collagen membranes placed on the dura and 24 patients without any material on the dura were included in the study. Postoperative MRI images of the patients with and without collagen membranes were examined and evaluated whether the material used was effective in preventing arachnoiditis and / or epidural fibrosis and granulation tissue formation. Results: Nine female patients (37.5%) and 15 male patients (62.5%) of 24 patients were in the collagen membrane-free group. Four of the patients in the collagen membrane group were female (25%) and 12 were male (75%). The mean age of the non-membrane group was 35.47 ± 9.06, and the mean age of the membrane group was 37.40 ± 8.92 years. According to MRI findings, granulation tissue and epidural fibrosis were not observed in 8 (50%) of 16 patients with collagen membranes, whereas granulation tissue was observed in 8 (50%) patients. Granulation tissue was not observed in 10 (41.7%) of 24 patients without collagen membrane, whereas epidural fibrosis and granulation tissue formation was observed in 14 (58.3%). Based on these results, there was no statistically significant relationship between type-I collagen membrane use and granulation tissue formation. (P = 0.604 <0.05). There was no difference between the rate of granulation tissue (50%) and absence (50%) in patients with type-I collagen membranes. Conclusion: According to these results and MRI findings, it was found that peroperative type-I collagen membrane use in lumbar discectomy did not have a statistically significant effect on granulation tissue or epidural fibrosis formation.https://dergipark.org.tr/tr/download/article-file/2942607lomber disk hernisiepidural fibroziskollajen membranmrglumbar disk herniationepidural fibrosiscollagen membranemri |
| spellingShingle | Mehmet Kaya The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings Genel Tıp Dergisi lomber disk hernisi epidural fibrozis kollajen membran mrg lumbar disk herniation epidural fibrosis collagen membrane mri |
| title | The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings |
| title_full | The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings |
| title_fullStr | The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings |
| title_full_unstemmed | The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings |
| title_short | The Assessment of the Effects of Synthetic Collagen Membrane Use on the Prevention of Epidural Fibrosis Development in Patients Undergoing Lumbar Discectomy by Magnetic Resonance Imaging Findings |
| title_sort | assessment of the effects of synthetic collagen membrane use on the prevention of epidural fibrosis development in patients undergoing lumbar discectomy by magnetic resonance imaging findings |
| topic | lomber disk hernisi epidural fibrozis kollajen membran mrg lumbar disk herniation epidural fibrosis collagen membrane mri |
| url | https://dergipark.org.tr/tr/download/article-file/2942607 |
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