Preoperative denosumab combined with microwave ablation for joint preservation in advanced giant cell tumor of bone: a retrospective study
Abstract Background Preoperative denosumab has been an essential part of the management of giant cell tumor of bone (GCTB) which enhanced subchondral bone integrity and facilitated joint preservation surgery. However, evidence suggests that denosumab-induced sclerotic changes may potentially increas...
Main Authors: | Chuanxi Zheng, Xiayi Zhou, Gang Xu, Jin Qiu, Tao Lan, Wei Li, Shiquan Zhang |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-025-05589-3 |
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