Preoperative denosumab combined with microwave ablation for joint preservation in advanced giant cell tumor of bone: a retrospective study

Abstract Background Preoperative denosumab has been an essential part of the management of giant cell tumor of bone (GCTB) which enhanced subchondral bone integrity and facilitated joint preservation surgery. However, evidence suggests that denosumab-induced sclerotic changes may potentially increas...

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Bibliographic Details
Main Authors: Chuanxi Zheng, Xiayi Zhou, Gang Xu, Jin Qiu, Tao Lan, Wei Li, Shiquan Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-025-05589-3

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