Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.

Immunodominance of HIV-1 specific CD8+ T-cell responses is related to disease progression rate in vertically infected adolescents.

HIV-1 vertically infected children in the USA are living into adolescence and beyond with the widespread use of antiretroviral drugs. These patients exhibit striking differences in the rate of HIV-1 disease progression which could provide insights into mechanisms of control. We hypothesized that dif...

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Bibliographic Details
Main Authors: Elizabeth R Sharp, Christian B Willberg, Peter J Kuebler, Jacob Abadi, Glenn J Fennelly, Joanna Dobroszycki, Andrew A Wiznia, Michael G Rosenberg, Douglas F Nixon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3139570?pdf=render

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