CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING
Liposomal form of adenosine-5-triphosphate (ATP) for oral applying was studied. The methods of obtaining and determining the size of the liposomes, the definition of ATP percentage content in liposomes were proposed. The effect of liposomal form of ATP on physical performance of laboratory animals b...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2013-06-01
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| Series: | Biotechnologia Acta |
| Subjects: | |
| Online Access: | http://biotechnology.kiev.ua/images/storage/no3_2013/khobatenko_3_2013.pdf |
| _version_ | 1797766856528887808 |
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| author | O. V. Khrobatenko N. V. Prytulska S. M. Shulga |
| author_facet | O. V. Khrobatenko N. V. Prytulska S. M. Shulga |
| author_sort | O. V. Khrobatenko |
| collection | DOAJ |
| description | Liposomal form of adenosine-5-triphosphate (ATP) for oral applying was studied. The methods of obtaining and determining the size of the liposomes, the definition of ATP percentage content in liposomes were proposed. The effect of liposomal form of ATP on physical performance of laboratory animals by swimming to the limit of exhaustion was studied. It was shown that using of the liposomal form as compared with free ATP (in a similar dose) promoted the increased efficiency of laboratory animals. Application of liposomal form occurring at single administration for 6 days at a dose of 30 mg/kg facilated a 62% increase of efficiency, and 60 mg/kg did 76%, while consumption of liposomal form of ATP for 12 days did 64% and 93%, respectively. |
| first_indexed | 2024-03-12T20:30:16Z |
| format | Article |
| id | doaj.art-67953a988981465b93e9901adfa3951d |
| institution | Directory Open Access Journal |
| issn | 2410-7751 2410-776X |
| language | English |
| last_indexed | 2024-03-12T20:30:16Z |
| publishDate | 2013-06-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | Biotechnologia Acta |
| spelling | doaj.art-67953a988981465b93e9901adfa3951d2023-08-02T00:05:10ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryBiotechnologia Acta2410-77512410-776X2013-06-016310011510.15407/biotech6.03.110CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYINGO. V. Khrobatenko0N. V. Prytulska1S. M. Shulga2Kyiv National University of Trade and Economics, UkraineKyiv National University of Trade and Economics, UkraineState Organization «Institute of Food Biotechnology and Genomics» of National Academy of Sciences of Ukraine, KyivLiposomal form of adenosine-5-triphosphate (ATP) for oral applying was studied. The methods of obtaining and determining the size of the liposomes, the definition of ATP percentage content in liposomes were proposed. The effect of liposomal form of ATP on physical performance of laboratory animals by swimming to the limit of exhaustion was studied. It was shown that using of the liposomal form as compared with free ATP (in a similar dose) promoted the increased efficiency of laboratory animals. Application of liposomal form occurring at single administration for 6 days at a dose of 30 mg/kg facilated a 62% increase of efficiency, and 60 mg/kg did 76%, while consumption of liposomal form of ATP for 12 days did 64% and 93%, respectively.http://biotechnology.kiev.ua/images/storage/no3_2013/khobatenko_3_2013.pdfliposomesliposomal form ATPphysical performance |
| spellingShingle | O. V. Khrobatenko N. V. Prytulska S. M. Shulga CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING Biotechnologia Acta liposomes liposomal form ATP physical performance |
| title | CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING |
| title_full | CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING |
| title_fullStr | CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING |
| title_full_unstemmed | CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING |
| title_short | CREATING AND INVESTIGATION OF ADENOSINE-5-TRIPHOSPHATE LIPOSOMAL FORMS FOR ORAL APPLYING |
| title_sort | creating and investigation of adenosine 5 triphosphate liposomal forms for oral applying |
| topic | liposomes liposomal form ATP physical performance |
| url | http://biotechnology.kiev.ua/images/storage/no3_2013/khobatenko_3_2013.pdf |
| work_keys_str_mv | AT ovkhrobatenko creatingandinvestigationofadenosine5triphosphateliposomalformsfororalapplying AT nvprytulska creatingandinvestigationofadenosine5triphosphateliposomalformsfororalapplying AT smshulga creatingandinvestigationofadenosine5triphosphateliposomalformsfororalapplying |