Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

Dysregulated host immune responses to infection often occur, leading to sepsis, multiple organ failure, and death. Some patients rapidly recover from sepsis, but many develop chronic critical illness (CCI), a debilitating condition that impacts functional outcomes and long-term survival. The “Persis...

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Bibliographic Details
Main Authors: Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, Hiroyuki Horiguchi, Scott C. Brakenridge, Anna Gardner, Philip A. Efron, Azra Bihorac, Mark Segal, Frederick A. Moore, Lyle L. Moldawer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Immunology
Subjects:
sepsis
inflammation
critical illness
PICS
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01511/full

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