Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure
Introduction: The use of stereological methods in evaluation of volume changes in vital organs such as kidney is very important. In this study, the volume of glomeruli in glycerol-induced acute renal failure in rats was determined. Methods: 48 Sprague-Dawley male rats were divided into 2 groups (1co...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | fas |
| Published: |
Shahid Sadoughi University of Medical Sciences
2005-10-01
|
| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| Subjects: | |
| Online Access: | http://jssu.ssu.ac.ir/browse.php?a_id=699&slc_lang=en&sid=1&ftxt=1 |
| _version_ | 1818176214471278592 |
|---|---|
| author | Sh Zahiri MR Panjehshahin AR Dezfulian F Dehghani |
| author_facet | Sh Zahiri MR Panjehshahin AR Dezfulian F Dehghani |
| author_sort | Sh Zahiri |
| collection | DOAJ |
| description | Introduction: The use of stereological methods in evaluation of volume changes in vital organs such as kidney is very important. In this study, the volume of glomeruli in glycerol-induced acute renal failure in rats was determined. Methods: 48 Sprague-Dawley male rats were divided into 2 groups (1control, 1experiment). Experimental group was injected 10ml/kg of 50% glycerol intramuscularly, while the same volume of saline was injected in the control group. After 48h, animals were dissected under deep anesthesia, and right kidneys were fixed by vascular perfusion. Microscopic slides were stained with H-E. Glomerular volumes were calculated using projecting microscope, point counting and cavalieri principal. Results: The results indicated that renal failure induced-glycerol didn’t affect the glomerular volume Conclusion: It seems that estimation of glomerular volume can not be a useful variable in identification of acute renal failure induced glycerol, but further investigations are needed to clarify the issue |
| first_indexed | 2024-12-11T20:12:38Z |
| format | Article |
| id | doaj.art-67a0802ee5ca46d0a41dcb78a6bfafe9 |
| institution | Directory Open Access Journal |
| issn | 2228-5741 2228-5733 |
| language | fas |
| last_indexed | 2024-12-11T20:12:38Z |
| publishDate | 2005-10-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd |
| spelling | doaj.art-67a0802ee5ca46d0a41dcb78a6bfafe92022-12-22T00:52:15ZfasShahid Sadoughi University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd2228-57412228-57332005-10-011347175Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal FailureSh ZahiriMR PanjehshahinAR DezfulianF DehghaniIntroduction: The use of stereological methods in evaluation of volume changes in vital organs such as kidney is very important. In this study, the volume of glomeruli in glycerol-induced acute renal failure in rats was determined. Methods: 48 Sprague-Dawley male rats were divided into 2 groups (1control, 1experiment). Experimental group was injected 10ml/kg of 50% glycerol intramuscularly, while the same volume of saline was injected in the control group. After 48h, animals were dissected under deep anesthesia, and right kidneys were fixed by vascular perfusion. Microscopic slides were stained with H-E. Glomerular volumes were calculated using projecting microscope, point counting and cavalieri principal. Results: The results indicated that renal failure induced-glycerol didn’t affect the glomerular volume Conclusion: It seems that estimation of glomerular volume can not be a useful variable in identification of acute renal failure induced glycerol, but further investigations are needed to clarify the issuehttp://jssu.ssu.ac.ir/browse.php?a_id=699&slc_lang=en&sid=1&ftxt=1KidneyStereologyMean Volume |
| spellingShingle | Sh Zahiri MR Panjehshahin AR Dezfulian F Dehghani Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd Kidney Stereology Mean Volume |
| title | Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure |
| title_full | Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure |
| title_fullStr | Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure |
| title_full_unstemmed | Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure |
| title_short | Estimation of Glomerular Volume in Rats with Glycerol-Induced Acute Renal Failure |
| title_sort | estimation of glomerular volume in rats with glycerol induced acute renal failure |
| topic | Kidney Stereology Mean Volume |
| url | http://jssu.ssu.ac.ir/browse.php?a_id=699&slc_lang=en&sid=1&ftxt=1 |
| work_keys_str_mv | AT shzahiri estimationofglomerularvolumeinratswithglycerolinducedacuterenalfailure AT mrpanjehshahin estimationofglomerularvolumeinratswithglycerolinducedacuterenalfailure AT ardezfulian estimationofglomerularvolumeinratswithglycerolinducedacuterenalfailure AT fdehghani estimationofglomerularvolumeinratswithglycerolinducedacuterenalfailure |