Effects of prenatal exposure to the 1944–45 Dutch famine and glucocorticoid receptor polymorphisms on later life PTSD susceptibility

Effects of prenatal exposure to the 1944–45 Dutch famine and glucocorticoid receptor polymorphisms on later life PTSD susceptibility

Background: Exposure to adversity in utero is thought to increase susceptibility to develop posttraumatic stress disorder (PTSD) following later life trauma, due to neurobiological programming effects during critical developmental periods. It remains unknown whether effects of prenatal adversity on...

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Bibliographic Details
Main Authors: Kayleigh D. Gultig, Susanne R. de Rooij, Charlotte E. Hilberdink, Miranda Olff, Tessa J. Roseboom, Mirjam van Zuiden
Format: Article
Language:English
Published: Taylor & Francis Group 2023-11-01
Series:European Journal of Psychotraumatology
Subjects:
ptsd
prenatal adversity
glucocorticoid receptor
nr3c1
hpa axis
trauma
cortisol
differential susceptibility
Online Access:http://dx.doi.org/10.1080/20008066.2023.2219075

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