Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study

The aim of this preliminary study is to develop a methodology to evaluate the vascularization of fetal brain in normal and abnormal canditions by three-dimensional sonography associated to Power Doppler (3DPD), with application of Virtual Organ Computer-aided Analysis (VOCAL) that allows to derive v...

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Main Authors: M. Oberto, P. Gaglioti, G. Oggè, E. Olearo, C. Pace, T. Trodos, G.L. Panattoni
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:Journal of Biological Research
Subjects:
Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/4693
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author M. Oberto
P. Gaglioti
G. Oggè
E. Olearo
C. Pace
T. Trodos
G.L. Panattoni
author_facet M. Oberto
P. Gaglioti
G. Oggè
E. Olearo
C. Pace
T. Trodos
G.L. Panattoni
author_sort M. Oberto
collection DOAJ
description The aim of this preliminary study is to develop a methodology to evaluate the vascularization of fetal brain in normal and abnormal canditions by three-dimensional sonography associated to Power Doppler (3DPD), with application of Virtual Organ Computer-aided Analysis (VOCAL) that allows to derive vascularization and flow indexes. In this connction, we propose a new method of standardization of the setting and the acquisition mode, choosing in different fetuses and at different gestational ages the same anatomical volumes, corresponding to five spherical regions of interest. In particular, tu study the overall vascularization of the fetal brain, we use a sphere with a diameter corresponding to the bi-parietal distance. To evaluate the regional vascularization, we identify four sampling spherical sites, two in each hemisphere. This standard technical approach according to correct morphological criteria allows to exclude from the analysis vascular territories external to the brain.
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spelling doaj.art-67a62532dc6348cd868694c3a91da9e02022-12-21T17:59:47ZengPAGEPress PublicationsJournal of Biological Research1826-88382284-02302011-01-0184110.4081/jbr.2011.46933840Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological studyM. ObertoP. GagliotiG. OggèE. OlearoC. PaceT. TrodosG.L. PanattoniThe aim of this preliminary study is to develop a methodology to evaluate the vascularization of fetal brain in normal and abnormal canditions by three-dimensional sonography associated to Power Doppler (3DPD), with application of Virtual Organ Computer-aided Analysis (VOCAL) that allows to derive vascularization and flow indexes. In this connction, we propose a new method of standardization of the setting and the acquisition mode, choosing in different fetuses and at different gestational ages the same anatomical volumes, corresponding to five spherical regions of interest. In particular, tu study the overall vascularization of the fetal brain, we use a sphere with a diameter corresponding to the bi-parietal distance. To evaluate the regional vascularization, we identify four sampling spherical sites, two in each hemisphere. This standard technical approach according to correct morphological criteria allows to exclude from the analysis vascular territories external to the brain.http://www.pagepressjournals.org/index.php/jbr/article/view/4693fetus, brain, vascularization, 3DPD sonography
spellingShingle M. Oberto
P. Gaglioti
G. Oggè
E. Olearo
C. Pace
T. Trodos
G.L. Panattoni
Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
Journal of Biological Research
fetus, brain, vascularization, 3DPD sonography
title Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
title_full Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
title_fullStr Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
title_full_unstemmed Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
title_short Sonographic evaluation of overall and regional vascularization of fetal brain: a preliminary methodological study
title_sort sonographic evaluation of overall and regional vascularization of fetal brain a preliminary methodological study
topic fetus, brain, vascularization, 3DPD sonography
url http://www.pagepressjournals.org/index.php/jbr/article/view/4693
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