Raising the bar on fibrinogen: a retrospective assessment of critical hypofibrinogenemia in severely injured trauma patients

Raising the bar on fibrinogen: a retrospective assessment of critical hypofibrinogenemia in severely injured trauma patients

Objectives Fibrinogen depletion may occur at higher levels than historically referenced. We evaluated hypofibrinogenemia and associated mortality and multiple organ failure (MOF) after severe injury.Methods Retrospective investigation including 417 adult patients with Injury Severity Score (ISS) &am...

Full description

Bibliographic Details
Main Authors:	Justin Richards, Thomas Scalea, Jonathan H Chow, Rosemary Kozar, Benjamin T Fedeles
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2023-08-01
Series:	Trauma Surgery & Acute Care Open
Online Access:	https://tsaco.bmj.com/content/8/1/e000937.full

Similar Items

Early Predictive Factors of Hypofibrinogenemia in Acute Trauma Patients
by: Shahram Paydar, et al.
Published: (2018-01-01)

Early administration of fibrinogen concentrate in patients with polytrauma with thromboelastometry suggestive of hypofibrinogenemia: A randomized feasibility trial
by: Lucas Siqueira de Lucena, et al.
Published: (2021-11-01)

Fibrinogen Columbus: a novel gamma Gly200Val mutation causing hypofibrinogenemia in a family with associated thrombophilia
by: Ryan L. Davis, et al.
Published: (2007-08-01)

Acquired hypofibrinogenemia: current perspectives
by: Besser MW, et al.
Published: (2016-09-01)

Clinical Characteristics of Hospitalized Neonates With Hypofibrinogenemia: A Retrospective Cohort Study
by: Weijun Zhou, et al.
Published: (2020-09-01)

Serum concentration as a predictor of tigecycline-induced hypofibrinogenemia in critically ill patients: A retrospective cohort study
by: Xiaoxuan Yang, et al.
Published: (2022-10-01)

Risk Factors for Tigecycline-Associated Hypofibrinogenemia
by: Liu J, et al.
Published: (2021-04-01)

A case of hypofibrinogenemia presenting with submental hamatoma
by: Mujahida Rahman, et al.
Published: (2016-08-01)

Fibrinogen metabolic responses to trauma
by: Martini Wenjun
Published: (2009-01-01)

Hypofibrinogenemia is an independent predictor of hemophagocytic lymphohistiocytosis in children with sepsis
by: Xin Luo, et al.
Published: (2023-10-01)

A Lesser Known Side Effect of Tigecycline: Hypofibrinogenemia
by: Fulya Yılmaz Duran, et al.
Published: (2018-02-01)

Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death
by: Yan Zhang MD, et al.
Published: (2020-03-01)

Incidence, characteristics and risk factors of hypofibrinogenemia associated with tigecycline: A multicenter retrospective study in China
by: Bing Leng, et al.
Published: (2022-10-01)

A Novel Nonsense Mutation in <i>FGB</i> (c.1421G>A; p.Trp474Ter) in the Beta Chain of Fibrinogen Causing Hypofibrinogenemia with Bleeding Phenotype
by: Tomas Simurda, et al.
Published: (2020-12-01)

Congenital Hypofibrinogenemia is a Potential Risk Factor for Ischemic Stroke
by: Demet Bölükbaşı, et al.
Published: (2024-11-01)

Preeclampsia complicated with hypofibrinogenemia: 2 case reports and review of the literature
by: Shiguang Li, et al.
Published: (2023-09-01)

Correlation between Maximum Clot Firmness in FIBTEM and Fibrinogen Level in Critical Trauma Patients
by: Supphamongkhon Khunakanan, et al.
Published: (2019-01-01)

Raising the Bar and Surpassing Expectations
by: Niles Reddick, et al.
Published: (2014-01-01)

Incidence and outcome of early acute kidney injury in critically-ill trauma patients.
by: Amber S Podoll, et al.
Published: (2013-01-01)

Prehospital balanced resuscitation may mitigate hypofibrinogenemia in traumatic hemorrhagic shock
by: Nichole Starr, et al.
Published: (2024-07-01)

Machine learning–based prediction model for hypofibrinogenemia after tigecycline therapy
by: Jianping Zhu, et al.
Published: (2024-10-01)

Prenatal and Peripartum Management of Patients with Hypofibrinogenemia Resulted in Two Successful Deliveries
by: Yuko Teraoka, et al.
Published: (2017-01-01)

Tocilizumab-induced hypofibrinogenemia in patients with systemic-onset juvenile idiopathic arthritis
by: Tingyan He, et al.
Published: (2023-06-01)

Acute myocardial infarction in a patient with hypofibrinogenemia: a case report
by: Mghaieth Fathia, et al.
Published: (2011-12-01)

Angiosarcoma of the breast with hypofibrinogenemia: A rare case report and review of the literature
by: Ran An, et al.
Published: (2022-11-01)

Hypofibrinogenemia following injury in 186 children and adolescents: identification of the phenotype, current outcomes, and potential for intervention
by: Charles E Wade, et al.
Published: (2023-08-01)

Defending human difference by raising the bar
by: Gough, J
Published: (2022)

Abe's India visit : raising the bar
by: Rupakiyoti Borah
Published: (2014)

Raising the bar in ulcerative colitis management
by: Fabrizio Fanizzi, et al.
Published: (2024-11-01)

Raising the bar – Sarcoma management in India
by: Srinath Gupta, et al.
Published: (2020-01-01)

Raising the BarCamp: international reflections
by: David Topps, et al.
Published: (2017-07-01)

Spontaneous vulvar hematoma as a rare manifestation of congenital hypofibrinogenemia. Case report
by: Sebastián Felipe Sierra-Umaña, et al.
Published: (2019-07-01)

Does an early, balanced resuscitation strategy reduce the incidence of hypofibrinogenemia in hemorrhagic shock?
by: Krislynn M Mueck, et al.
Published: (2024-04-01)

A novel mutation in the FGG gene causes hypofibrinogenemia in a Chinese family
by: Xiaoying Xie, et al.
Published: (2024-02-01)

Pediatric Fibrinogen PART II—Overview of Indications for Fibrinogen Use in Critically Ill Children
by: Gemma Louise Crighton, et al.
Published: (2021-04-01)

Raising the bar on the evaluation of out-of-distribution detection
by: Mukhoti, J, et al.
Published: (2023)

Raise the bar : strengthening the civil engineering profession /
by: Russell, Jeffrey S., editor, et al.
Published: (2013)

Raising the bar on sex and gender reporting in research
Published: (2022-05-01)

Adherence to the transfer recommendations of the German Trauma Society in severely injured children: a retrospective study from the TraumaRegister DGU
by: Felix Marius Bläsius, et al.
Published: (2023-07-01)

Thromboelastography as an early prediction method for hypofibrinogenemia in emergency department patients with primary postpartum hemorrhage
by: Sang-Min Kim, et al.
Published: (2024-09-01)