Mucinous urothelial carcinoma of the renal pelvis
Urothelial carcinoma with abundant myxoid stroma is a newly-described and extremely rare entity. Since only very few cases have been reported, there is no consensus on its nomenclature. Microscopic examination revealed invasive urothelial carcinoma with widespread low-grade noninvasive areas. There...
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Format: | Article |
Language: | English |
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SAGE Publishing
2014-12-01
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Series: | Rare Tumors |
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Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/5485 |
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author | Kemal Behzatoğlu Ceren Boyacı Oğuzhan Okçu Ezgi Hacıhasanoğlu Yasemin Çakır Seher Darakçı |
author_facet | Kemal Behzatoğlu Ceren Boyacı Oğuzhan Okçu Ezgi Hacıhasanoğlu Yasemin Çakır Seher Darakçı |
author_sort | Kemal Behzatoğlu |
collection | DOAJ |
description | Urothelial carcinoma with abundant myxoid stroma is a newly-described and extremely rare entity. Since only very few cases have been reported, there is no consensus on its nomenclature. Microscopic examination revealed invasive urothelial carcinoma with widespread low-grade noninvasive areas. There were focal invasive areas in the neighborhood of the renal parenchyma. Malignant urothelial tumor/cell groups localized in the stroma had abundant myxoid/mucinous background in the invasive areas. The cytoplasm of the tumoral cells was more eosinophilic in these areas and the cells formed small groups and cords. Histochemically, PAS and Alcian Blue were positive in the cytoplasm of the tumoral cells and in the stroma while negative in the non-mucinous areas. Immunohistochemically, the tumoral cells of the mucinous invasive areas diffusely expressed MUC1 and MUC2. We discuss the origin of the mucinous/myxoid stroma, the tumor’s nature and its nomenclature with histochemical and immunohistochemical features. |
first_indexed | 2024-12-13T15:40:40Z |
format | Article |
id | doaj.art-67aad33074084f0cb0298c9603a1ee67 |
institution | Directory Open Access Journal |
issn | 2036-3605 2036-3613 |
language | English |
last_indexed | 2024-12-13T15:40:40Z |
publishDate | 2014-12-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Rare Tumors |
spelling | doaj.art-67aad33074084f0cb0298c9603a1ee672022-12-21T23:39:50ZengSAGE PublishingRare Tumors2036-36052036-36132014-12-016410.4081/rt.2014.54852962Mucinous urothelial carcinoma of the renal pelvisKemal Behzatoğlu0Ceren Boyacı1Oğuzhan Okçu2Ezgi Hacıhasanoğlu3Yasemin Çakır4Seher Darakçı5Department of Pathology, Istanbul Education and Research Hospital, IstanbulDepartment of Pathology, Istanbul Education and Research Hospital, IstanbulDepartment of Pathology, Istanbul Education and Research Hospital, IstanbulDepartment of Pathology, Istanbul Education and Research Hospital, IstanbulDepartment of Pathology, Istanbul Education and Research Hospital, IstanbulDepartment of Pathology, Istanbul Education and Research Hospital, IstanbulUrothelial carcinoma with abundant myxoid stroma is a newly-described and extremely rare entity. Since only very few cases have been reported, there is no consensus on its nomenclature. Microscopic examination revealed invasive urothelial carcinoma with widespread low-grade noninvasive areas. There were focal invasive areas in the neighborhood of the renal parenchyma. Malignant urothelial tumor/cell groups localized in the stroma had abundant myxoid/mucinous background in the invasive areas. The cytoplasm of the tumoral cells was more eosinophilic in these areas and the cells formed small groups and cords. Histochemically, PAS and Alcian Blue were positive in the cytoplasm of the tumoral cells and in the stroma while negative in the non-mucinous areas. Immunohistochemically, the tumoral cells of the mucinous invasive areas diffusely expressed MUC1 and MUC2. We discuss the origin of the mucinous/myxoid stroma, the tumor’s nature and its nomenclature with histochemical and immunohistochemical features.http://www.pagepress.org/journals/index.php/rt/article/view/5485mucinous, myxoid, urothelial carcinoma, renal pelvis, MUCs |
spellingShingle | Kemal Behzatoğlu Ceren Boyacı Oğuzhan Okçu Ezgi Hacıhasanoğlu Yasemin Çakır Seher Darakçı Mucinous urothelial carcinoma of the renal pelvis Rare Tumors mucinous, myxoid, urothelial carcinoma, renal pelvis, MUCs |
title | Mucinous urothelial carcinoma of the renal pelvis |
title_full | Mucinous urothelial carcinoma of the renal pelvis |
title_fullStr | Mucinous urothelial carcinoma of the renal pelvis |
title_full_unstemmed | Mucinous urothelial carcinoma of the renal pelvis |
title_short | Mucinous urothelial carcinoma of the renal pelvis |
title_sort | mucinous urothelial carcinoma of the renal pelvis |
topic | mucinous, myxoid, urothelial carcinoma, renal pelvis, MUCs |
url | http://www.pagepress.org/journals/index.php/rt/article/view/5485 |
work_keys_str_mv | AT kemalbehzatoglu mucinousurothelialcarcinomaoftherenalpelvis AT cerenboyacı mucinousurothelialcarcinomaoftherenalpelvis AT oguzhanokcu mucinousurothelialcarcinomaoftherenalpelvis AT ezgihacıhasanoglu mucinousurothelialcarcinomaoftherenalpelvis AT yasemincakır mucinousurothelialcarcinomaoftherenalpelvis AT seherdarakcı mucinousurothelialcarcinomaoftherenalpelvis |