The Role of Neural Crest Cells in Development and Formation of Ear and Eye

Neural crest cells, as vertebrate-specific multipotent migratory stem cells, play a vital role in development of many embryonic organs. These cells dispart from the dorsal part of developing neural tube and then, migrate to different parts of the body, contributing to the formation of verity structu...

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Main Authors: Shahin Rouhi, Hossein Salehi, Noushin Amirpour
Format: Article
Language:fas
Published: Isfahan University of Medical Sciences 2016-01-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/5333
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author Shahin Rouhi
Hossein Salehi
Noushin Amirpour
author_facet Shahin Rouhi
Hossein Salehi
Noushin Amirpour
author_sort Shahin Rouhi
collection DOAJ
description Neural crest cells, as vertebrate-specific multipotent migratory stem cells, play a vital role in development of many embryonic organs. These cells dispart from the dorsal part of developing neural tube and then, migrate to different parts of the body, contributing to the formation of verity structures. In the head region of vertebrate, a population of neural crest cells migrates to the pharyngeal arch and periocular mesenchyme and makes critical contribution to the developing ear and eye. Understanding the contribution of neural crest cells in formation of these important sense organs is relevant both for basic science knowledge and human clinical concern. As there was no comprehensive review on neural crest cells function in ear and eye developing, we aimed to review the studies on the role of neural crest cells in development and formation of ear and eye.
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spelling doaj.art-67ad8cfdd94445078821fb9c97f893712023-09-02T10:09:54ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2016-01-0133358194319522068The Role of Neural Crest Cells in Development and Formation of Ear and EyeShahin Rouhi0Hossein Salehi1Noushin Amirpour2Department of Tissue Engineering, School of Basic Sciences, Najafabad Branch, Islamic Azad University, Isfahan, IranAssistant Professor, Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranAssistant Professor, Department of Anatomical Sciences, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IranNeural crest cells, as vertebrate-specific multipotent migratory stem cells, play a vital role in development of many embryonic organs. These cells dispart from the dorsal part of developing neural tube and then, migrate to different parts of the body, contributing to the formation of verity structures. In the head region of vertebrate, a population of neural crest cells migrates to the pharyngeal arch and periocular mesenchyme and makes critical contribution to the developing ear and eye. Understanding the contribution of neural crest cells in formation of these important sense organs is relevant both for basic science knowledge and human clinical concern. As there was no comprehensive review on neural crest cells function in ear and eye developing, we aimed to review the studies on the role of neural crest cells in development and formation of ear and eye.http://jims.mui.ac.ir/index.php/jims/article/view/5333Neural crest cellsEarEyeDevelopment
spellingShingle Shahin Rouhi
Hossein Salehi
Noushin Amirpour
The Role of Neural Crest Cells in Development and Formation of Ear and Eye
مجله دانشکده پزشکی اصفهان
Neural crest cells
Ear
Eye
Development
title The Role of Neural Crest Cells in Development and Formation of Ear and Eye
title_full The Role of Neural Crest Cells in Development and Formation of Ear and Eye
title_fullStr The Role of Neural Crest Cells in Development and Formation of Ear and Eye
title_full_unstemmed The Role of Neural Crest Cells in Development and Formation of Ear and Eye
title_short The Role of Neural Crest Cells in Development and Formation of Ear and Eye
title_sort role of neural crest cells in development and formation of ear and eye
topic Neural crest cells
Ear
Eye
Development
url http://jims.mui.ac.ir/index.php/jims/article/view/5333
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