The clinicopathological characteristics and differential diagnosis of histiocytosis

<p>The histiocytosis is divided into Langerhans' cell histiocytosis (histiocytosis X) and non-Langerhans' cell histiocytosis (NLCH). The former mainly occurs in lymphatic hematopoietic tissue and often involves central nervous system (CNS). The latter includes Rosai-Dorfman diseas...

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Main Author: Shi-zhu YU
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2015-04-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1169
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author Shi-zhu YU
author_facet Shi-zhu YU
author_sort Shi-zhu YU
collection DOAJ
description <p>The histiocytosis is divided into Langerhans' cell histiocytosis (histiocytosis X) and non-Langerhans' cell histiocytosis (NLCH). The former mainly occurs in lymphatic hematopoietic tissue and often involves central nervous system (CNS). The latter includes Rosai-Dorfman disease (RDD), hemophagocytic lymphohistiocytosis (HLH), Erdheim-Chester disease (ECD), juvenile xanthogranuloma (JXG) and xanthoma disseminatum (XD), choroid plexus xanthogranuloma (CPXG), choroid plexus xanthoma (CPX), which may occur in lymphatic hematopoietic tissue and (or) CNS. This review has briefly introduced the clinicopathological characteristics and differential diagnosis of the above lesions. The incidence of these diseases is low in CNS, so they are often ignored, misdiagnosed and impertinently treated by neurosurgeons and pathologists. Therefore, understanding their clinical and pathological characteristics is conducive to improve the diagnosis and therapy.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2015.04.002</p>
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spelling doaj.art-67aeaff2d3794b93a146c4a493c025352022-12-21T19:11:23ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312015-04-011542562621163The clinicopathological characteristics and differential diagnosis of histiocytosisShi-zhu YU0Department of Neuropathology, Tianjin Medical University General Hospital; Tianjin Neurological Institute; Tianjin Key Laboratory of Injury, Variation and Regeneration of Nervous System; Key Laboratory of Post-trauma Neuro-repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin 300052, China<p>The histiocytosis is divided into Langerhans' cell histiocytosis (histiocytosis X) and non-Langerhans' cell histiocytosis (NLCH). The former mainly occurs in lymphatic hematopoietic tissue and often involves central nervous system (CNS). The latter includes Rosai-Dorfman disease (RDD), hemophagocytic lymphohistiocytosis (HLH), Erdheim-Chester disease (ECD), juvenile xanthogranuloma (JXG) and xanthoma disseminatum (XD), choroid plexus xanthogranuloma (CPXG), choroid plexus xanthoma (CPX), which may occur in lymphatic hematopoietic tissue and (or) CNS. This review has briefly introduced the clinicopathological characteristics and differential diagnosis of the above lesions. The incidence of these diseases is low in CNS, so they are often ignored, misdiagnosed and impertinently treated by neurosurgeons and pathologists. Therefore, understanding their clinical and pathological characteristics is conducive to improve the diagnosis and therapy.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2015.04.002</p>http://www.cjcnn.org/index.php/cjcnn/article/view/1169HistiocytosisLangerhans cellsNon-Langerhans histiocytesPathologyDiagnosis, differential
spellingShingle Shi-zhu YU
The clinicopathological characteristics and differential diagnosis of histiocytosis
Chinese Journal of Contemporary Neurology and Neurosurgery
Histiocytosis
Langerhans cells
Non-Langerhans histiocytes
Pathology
Diagnosis, differential
title The clinicopathological characteristics and differential diagnosis of histiocytosis
title_full The clinicopathological characteristics and differential diagnosis of histiocytosis
title_fullStr The clinicopathological characteristics and differential diagnosis of histiocytosis
title_full_unstemmed The clinicopathological characteristics and differential diagnosis of histiocytosis
title_short The clinicopathological characteristics and differential diagnosis of histiocytosis
title_sort clinicopathological characteristics and differential diagnosis of histiocytosis
topic Histiocytosis
Langerhans cells
Non-Langerhans histiocytes
Pathology
Diagnosis, differential
url http://www.cjcnn.org/index.php/cjcnn/article/view/1169
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