Structural and (Pseudo-)Enzymatic Properties of Neuroglobin: Its Possible Role in Neuroprotection

Structural and (Pseudo-)Enzymatic Properties of Neuroglobin: Its Possible Role in Neuroprotection

Neuroglobin (Ngb), the third member of the globin family, was discovered in human and murine brains in 2000. This monomeric globin is structurally similar to myoglobin (Mb) and hemoglobin (Hb) α and β subunits, but it hosts a bis-histidyl six-coordinated heme-Fe atom. Therefore, the heme-based react...

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Bibliographic Details
Main Authors: Giovanna De Simone, Diego Sbardella, Francesco Oddone, Alessandra Pesce, Massimo Coletta, Paolo Ascenzi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
neuroglobin
structure
reactivity
(pseudo-)enzymatic properties
neuroprotection
retina
Online Access:https://www.mdpi.com/2073-4409/10/12/3366

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