Genotoxic, neurotoxic and neuroprotective activities of apomorphine and its oxidized derivative 8-oxo-apomorphine

Genotoxic, neurotoxic and neuroprotective activities of apomorphine and its oxidized derivative 8-oxo-apomorphine

Apomorphine is a dopamine receptor agonist proposed to be a neuroprotective agent in the treatment of patients with Parkinson's disease. Both in vivo and in vitro studies have shown that apomorphine displays both antioxidant and pro-oxidant actions, and might have either neuroprotective or neur...

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Bibliographic Details
Main Authors:	J.N. Picada, R. Roesler, J.A.P. Henriques
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2005-04-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Apomorphine 8-Oxo-apomorphine- semiquinone Dopamine Genotoxicity Neurotoxicity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000400001

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