Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis

Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis

Abstract Background Previously, we and others have reported higher populations of circulating neutrophils in patients with neovascular age-related macular degeneration (nAMD). Neutrophil gelatinase-associated lipocalin (NGAL, also known as lipocalin-2, LCN2), an important innate immune mediator, is...

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Bibliographic Details
Main Authors: Mei Chen, Nan Yang, Judith Lechner, Levente Toth, Ruth Hogg, Giuliana Silvestri, Usha Chakravarthy, Heping Xu
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Immunity & Ageing
Subjects:
Age-related macular degeneration
Inflammation
Neutrophils
Lipocalin 2
Matrix metalloproteinase
Macular fibrosis
Online Access:http://link.springer.com/article/10.1186/s12979-020-00205-w

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