Developmental progression of DNA double-strand break repair deciphered by a single-allele resolution mutation classifier

Developmental progression of DNA double-strand break repair deciphered by a single-allele resolution mutation classifier

Abstract DNA double-strand breaks (DSBs) are repaired by a hierarchically regulated network of pathways. Factors influencing the choice of particular repair pathways, however remain poorly characterized. Here we develop an Integrated Classification Pipeline (ICP) to decompose and categorize CRISPR/C...

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Bibliographic Details
Main Authors: Zhiqian Li, Lang You, Anita Hermann, Ethan Bier
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46479-2

Internet

https://doi.org/10.1038/s41467-024-46479-2

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